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Synthesis and Biological Investigation of some Novel Sulfonamide and Amide Derivatives Containing Coumarin Moieties
New sulfonamide and amide derivatives containing coumarin moieties; oxo-2H-chromen-sulfamoylphenylacetamides and oxo-2H-chromen-arylacetamides were synthesized starting from diverse 2-chloroacetamideExpand
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Curcumin-loaded guanidine functionalized PEGylated I3ad mesoporous silica nanoparticles KIT-6: practical strategy for the breast cancer therapy.
In this research, we have synthesized guanidine functionalized PEGylated mesoporous silica nanoparticles as a novel and efficient drug delivery system (DDS). For this purpose, guanidineExpand
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Novel Tacrine‐Based Pyrano[3’,4’:5,6]pyrano[2,3‐b]quinolinones: Synthesis and Cholinesterase Inhibitory Activity
In order to develop effective anti‐cholinesterase compounds, a novel series of pyrano[3’,4’:5,6]pyrano[2,3‐b]quinolinones were designed, synthesized, and evaluated in vitro againstExpand
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K7[PW11CoO40]-catalyzed one-pot synthesis of polyhydroquinoline derivatives via the Hantzsch three component condensation
The synthesis of various polyhydroquinoline derivatives has been achieved using catalytic amounts of green, inexpensive and eco-friendly Keggin type heteropolyacid. The products were obtained in highExpand
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Synthesis and Biological Activity of Some Benzochromenoquinolinones: Tacrine Analogs as Potent Anti‐Alzheimer's Agents
Alzheimer's disease (AD) is a well‐known neurodegenerative disorder affecting millions of old people worldwide and the corresponding epidemiological data emphasize the importance of the disease. AsExpand
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Novel quinazolin‐4(3H)‐one linked to 1,2,3‐triazoles: Synthesis and anticancer activity
In this work, a wide range of novel quinazolin‐4(3H)‐one linked to 1,2,3‐triazoles was designed, synthesized, and evaluated against a panel of three human breast (MDA‐MB‐231, MCF‐7, T‐47D), lungExpand
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In vitro cholinesterase inhibitory activity of some plants used in Iranian traditional medicine
Abstract In this study, in vitro evaluation of cholinesterase inhibitory (ChEI) activity of various plants including betel nuts (Areca catechu L.), clove buds (Syzygium aromaticum L.), aerial partsExpand
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EVALUATING THE ACCUMULATION TREND OF L-DOPA IN DARK-GERMINATED SEEDS AND SUSPENSION CULTURES OF Phaseolus vulgaris L. BY AN EFFICIENT UV-SPECTROPHOTOMETRIC METHOD
Samira Rahmani-Nezhada, Shima Dianata, Mina Saeedia,b, Maliheh Barazandeh Tehranic, Adel Ghadirid and Abbas Hadjiakhoondia,e,* Medicinal Plants Research Center, Faculty of Pharmacy, Tehran UniversityExpand
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A review on tacrine-based scaffolds as multi-target drugs (MTDLs) for Alzheimer's disease.
Alzheimer's disease (AD) is a multifactorial neurological disorder among elderly people and combinatorial factors such as genetic, lifestyle, and environmental are involved in onset and diseaseExpand
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