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Crocin triggers the apoptosis through increasing the Bax/Bcl-2 ratio and caspase activation in human gastric adenocarcinoma, AGS, cells.
Insight is provided into the molecular mechanisms underlying the crocin-induced apoptosis in the AGS cells, rendering it as the potential anticancer agent.
MicroRNA-100 shuttled by mesenchymal stem cell-derived exosomes suppresses in vitro angiogenesis through modulating the mTOR/HIF-1α/VEGF signaling axis in breast cancer cells
The findings suggest that exosomal transfer of miR-100 may be a novel mechanism underlying the paracrine effects of MSC-derived exosomes and may provide a means by which these vesicles can modulate vascular responses within the microenvironment of breast cancer cells.
Up-regulation of HOTAIR long non-coding RNA in human gastric adenocarcinoma tissues
Aberrant up-regulation of HOTAIR is found in gastric adenocarcinoma samples compared with normal adjacent gastric epithelium tissues and this result suggests a role for HotaIR long non-coding RNA in Gastric cancer progression.
Characterization of a pH and detergent-tolerant, cold-adapted type I pullulanase from Exiguobacterium sp. SH3
Pul-SH3 with several industrially important characteristics seems desirable for cold hydrolysis of starch, and was characterized to be a cold-adapted type I pullulanase with maximum activity at 45 °C.
Identification and Classification of Main Iranian Olive Cultivars Using Microsatellite Markers
The existence of homonyms, synonyms, or mislabeling as well as intracultivar polymorphism was revealed by allele differences between accessions of the same denomination, but most accessions with the same generic names were grouped together.
Detection of icaAD Gene and Biofilm Formation in Staphylococcus aureus Isolates from Wound Infections
The ability of S.aureus to form biofilms helps the bacterium to survive hostile environments within the host, suggests that biofilm production is a risk factor for infection.
The Influence of Insertion of a Critical Residue (Arg356) in Structure and Bioluminescence Spectra of Firefly Luciferase*
The construction and purification of a mutant at residue Arg356, which is not conserved in beetle luciferases is reported, which might make mutant luciferase a suitable reporter for the study of gene expression and bioluminescence imaging.