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Antimicrobial activity of the bufadienolides marinobufagin and telocinobufagin isolated as major components from skin secretion of the toad Bufo rubescens.
Two antimicrobial bufadienolides were isolated from skin secretions of the Brazilian toad Bufo rubescens and promoted an increase of the contraction force in isolated frog ventricle strips. Expand
Plant defense and antimicrobial peptides.
The main groups of antimicrobial peptides found in plants are thionins, defensins and lipid transfer proteins, which constitute interesting candidates to engineer disease resistance in plants. Expand
Disintegrins from Snake Venoms and their Applications in Cancer 
Research and Therapy
The relationship of integrins with cancer is highlighted and examples as to how certain disintegrins can detect and affect biological processes related to cancer are presented to illustrate the great potential of these molecules for cancer research. Expand
Proteomic landscape of seminal plasma associated with dairy bull fertility
The present study analyzed the seminal fluid proteome of Bos taurus and potential associations between proteins and fertility scores to represent a major and novel contribution to the study of bovine seminal proteins. Expand
NetWheels: A web application to create high quality peptide helical wheel and net projections
A web-based application has been developed that has several futures to create, customize and export these projections and is freely available at http://lbqp.unb.br/NetWheels. Expand
Purification and characterization of a small (7.3 kDa) putative lipid transfer protein from maize seeds.
The present study reports, for the first time in literature, the purification and biochemical characterization of a small basic protein from maize seeds similar to plant lipid transfer proteins-2, named mLTP2, which exhibits high sequence similarity with other plant LTP2s previously described. Expand
Cytotoxic Activity and Antiproliferative Effects of Crude Skin Secretion from Physalaemus nattereri (Anura: Leptodactylidae) on in vitro Melanoma Cells
The results demonstrated that the crude secretion reduced the viability of B16F10 cells, causing changes in cell morphology, reduction in mitochondrial membrane potential, increase in phosphatidylserine exposure, and cell cycle arrest in S-phase, suggesting that tumor cells die by apoptosis. Expand
Antimicrobial peptides from anurans skin secretions.
An overview of antimicrobial peptides found in anurans skin secretions, which constitute an initial barrier against microbial infections because of their activity against a large array of microorganisms. Expand
Hylin a1, the first cytolytic peptide isolated from the arboreal South American frog Hypsiboas albopunctatus (“spotted treefrog”)
RP-HPLC fractionation of the electrically stimulated skin secretion of the arboreal South American frog Hypsiboas albopunctatus led to the isolation of a cytolytic C-terminally amidated peptide, named hylin a1 (Hy-a1), which displayed broad-spectrum antimicrobial activity against Gram-negative and Gram-positive bacteria. Expand
Composition of indolealkylamines of Bufo rubescens cutaneous secretions compared to six other Brazilian bufonids with phylogenetic implications.
Clear variation was observed in the composition of indolealkylamines of the cutaneous secretions studied and also between those found in the skin and parotoid gland secretions of the same species. Expand