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A marine natural product inhibitor of kinesin motors.
Members of the kinesin superfamily of motor proteins are essential for mitotic and meiotic spindle organization, chromosome segregation, organelle and vesicle transport, and many other processes that… Expand
Adociasulfates 1-6, Inhibitors of Kinesin Motor Proteins from the Sponge Haliclona (aka Adocia) sp.
- C. L. Blackburn, C. Hopmann, R. Sakowicz, M. S. Berdelis, L. Goldstein, D. Faulkner
- Chemistry, Medicine
- The Journal of organic chemistry
- 2 July 1999
Adociasulfates 1-6 (1-6) were isolated from an extract of the Palauan sponge Haliclona (aka Adocia) sp. that inhibited the transport of stabilized microtubules by the motor protein kinesin, which was… Expand