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The role of inflammatory cytokines and nitric oxide in the pathogenesis of necrotizing enterocolitis.
PURPOSE The role of inflammatory cytokines in the pathogenesis of necrotizing enterocolitis (NEC) is still undefined. Elevated levels of interleukin (IL)-6 and tumor necrosis factor (TNF)-alpha haveExpand
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Incarcerated and strangulated hernias in children. A statistical study of high-risk factors.
Incarceration and strangulation of the commonplace indirect inguinal hernia is still a significant management problem in children. We have studied a series of 2,764 consecutive patients operated uponExpand
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The patent processus vaginalis and the inguinal hernia.
Abstract In 1955 Rothenberg and Barnett 1 reported 50 infants and children with unilateral inguinal hernias who had contralateral groin explorations. They concluded that 100 per cent of infants underExpand
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Chest injuries in childhood.
Differences in anatomy and mechanisms of injury are believed to contribute to the unique response of children to thoracic trauma. To characterize the scope and consequences of childhood chest injury,Expand
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Transplantation of multiple abdominal viscera.
Two children with the short-gut syndrome and secondary liver failure were treated with evisceration and transplantation en bloc of the stomach, small intestine, colon, pancreas, and liver. The firstExpand
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Pathogenesis of pancreatic sepsis.
Although pancreatic sepsis is the most common cause of major morbidity and mortality associated with acute pancreatitis, the pathogenesis of such infections is unknown. Since intraperitoneal foci ofExpand
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Necrotizing enterocolitis in the extremely low birth weight infant.
Improved neonatal management has resulted in an enlarging population of extremely low birth weight (ELBW) infants. These infants have a high incidence of necrotizing enterocolitis (NEC) and a highExpand
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Is computed tomography a useful adjunct to the clinical examination for the diagnosis of pediatric gastrointestinal perforation from blunt abdominal trauma in children?
Perforations of the gastrointestinal (GI) tract, compared to solid organ injuries, are a relatively infrequent sequela of blunt abdominal trauma in children. The purpose of this study is to reviewExpand
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Breath hydrogen excretion as a screening test for the early diagnosis of necrotizing enterocolitis.
We measured breath H2 excretion in 122 neonates from birth to 1 month of age. The patients weighed less than 2000 g at birth and thus were at risk for developing necrotizing enterocolitis (NEC).Expand
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