M. Rosenthale

Publications81
h-index18
Citations1,246
Highly Influential Citations12
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Tepoxalin: a dual cyclooxygenase/5-lipoxygenase inhibitor of arachidonic acid metabolism with potent anti-inflammatory activity and a favorable gastrointestinal profile.
Tepoxalin [5-(4-chlorophenyl)-N-hydroxy-(4-methoxyphenyl)-N-methyl-1H- pyrazole-3-propanamide] is a potent inhibitor of sheep seminal vesicle cyclooxygenase (CO) (IC50 = 4.6 microM), rat basophilic… Expand
  • 129
  • 2
Animal pharmacology of Wy-16,225, a new analgesic agent.
The analgesic potency of Wy-16,225 in rodents and primates is greater than morphine while antagonist potency is slightly less than that of nalorphine. The compound demonstrates properties unlike… Expand
  • 47
  • 2
In vitro and in vivo antibacterial activities of levofloxacin (l-ofloxacin), an optically active ofloxacin.
The antibacterial activity of levofloxacin was compared with those of ofloxacin, ciprofloxacin, and other antibiotics. In general, levofloxacin was equally active or up to fourfold more active than… Expand
  • 194
  • 1
Effect of Anti-Inflammatory Agents on Acute Experimental Synovitis In Dogs
Summary Oral administration of the non-steroidal anti-inflammatory agents phenyl-butazone and indomethacin prevented or reversed a urate-induced synovitis in unanes-thetized dogs. Acetylsalicylic… Expand
  • 38
  • 1
Chemotherapy of experimental allergic encephalomyelitis (EAE).
  • 29
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Anticandidal activities of terconazole, a broad-spectrum antimycotic.
Terconazole is a new triazole ketal derivative with broad-spectrum in vitro and in vivo antifungal activities. This study further characterizes the effects of terconazole in vitro on yeast cell… Expand
  • 21
  • 1
The antialgesic drugs: Human therapeutic correlates of their potency in laboratory animal models of hyperalgesia
This survey discusses the correlation between the oral potency of antialgesic drugs in several pharmacology laboratories and their human oral dose in clinical practice. We also present a brief… Expand
  • 27
  • 1
A comparative study of the Lewis and Sprague Dawley rat in adjuvant arthritis.
  • M. Rosenthale
  • Medicine
  • Archives internationales de pharmacodynamie et de…
  • 1970
  • 22
  • 1
Adjuvant arthritis: immunopathological and hyperalgesic features.
Adjuvant arthritis is an experimental immunopathy that is thought to share many features of human rheumatoid arthritis and, as such, is one of the most widely used models for studying the… Expand
  • 18
  • 1
In Vitro and In Vivo Antibacterial Activities of Levofloxacin (l-Ofloxacin), an Optically Active Ofloxacin
  • 12
  • 1