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Decoding Somatic Driver Gene Mutations and Affected Signaling Pathways in Human Medulloblastoma Subgroups
- C. J. Robbins, Mayassa J. Bou-Dargham, Kevin Sanchez, M. Rosen, Q. Sang
- BiologyJournal of Cancer
- 17 November 2018
This study obtained medulloblastoma data from the Catalogue of Somatic Mutations in Cancer (COSMIC), which contains distinct samples that were not previously studied in a large cohort of patients, and identified somatic driver gene mutations and the signaling pathways affected by these driver genes for medullo-subgroups using bioinformatics tools.
Breast cancer mortality in Sweden.
Immune responses to CCAR1 and other dermatomyositis autoantigens are associated with attenuated cancer emergence
- D. Fiorentino, C. Mecoli, L. Casciola-Rosen
- Medicine, BiologyThe Journal of clinical investigation
- 18 January 2022
As the diversity of immune responses in anti–TIF1-γ DM patients increases, the likelihood of cancer emerging decreases, and the frequency of cancer decreased.
Abstract A128: Protective effects of nexrutine, a phellodendron amurense extract, against breast cancer is associated with autophagy.
Nexrutine is an herbal extract from the Chinese tree phellodendron amurense that has been used over hundreds of years in traditional Chinese medicine for treatment of inflammation, gastroenteritis, abdominal pain, and diarrhea and it is proposed that the use of nex rutine could provide a novel approach for protection against breast cancer.