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Long-Term Experimental Evolution in Escherichia coli. I. Adaptation and Divergence During 2,000 Generations
We assess the degree to which adaptation to a uniform environment among independently evolving asexual populations is associated with increasing divergence of those populations. In addition, we areExpand
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Long-term experimental evolution in Escherichia coli
-We assess the degree to which adaptation to a uniform environment among independently evolving asexual populations is associated with increasing divergence of those populations. In addition, we areExpand
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LABORATORY EVOLUTION OF POSTPONED SENESCENCE IN DROSOPHILA MELANOGASTER
  • M. Rose
  • Biology, Medicine
  • Evolution; international journal of organic…
  • 1 September 1984
Evolutionary genetics seems to have found the fundamental cause of senescence: the decline in the sensitivity of natural selection to gene effects expressed at later ages in most populations ofExpand
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Physiological mechanisms of evolved desiccation resistance in Drosophila melanogaster.
We investigated physiological characters associated with water balance in laboratory populations of Drosophila melanogaster selected for resistance to desiccating conditions for over 100 generations.Expand
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Genome-wide analysis of a long-term evolution experiment with Drosophila
Experimental evolution systems allow the genomic study of adaptation, and so far this has been done primarily in asexual systems with small genomes, such as bacteria and yeast. Here we presentExpand
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Evolution of senescence: late survival sacrificed for reproduction.
  • T. Kirkwood, M. Rose
  • Biology, Medicine
  • Philosophical transactions of the Royal Society…
  • 29 April 1991
In so far as it is associated with declining fertility and increasing mortality, senescence is directly detrimental to reproductive success. Natural selection should therefore act in the direction ofExpand
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COMPLEX TRADE‐OFFS AND THE EVOLUTION OF STARVATION RESISTANCE IN DROSOPHILA MELANOGASTER
The measurement of trade‐offs may be complicated when selection exploits multiple avenues of adaptation or multiple life‐cycle stages. We surveyed 10 populations of Drosophila melanogaster selectedExpand
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Metabolic Reserves and Evolved Stress Resistance in Drosophila melanogaster
We have examined starvation and desiccation resistance in 43 outbred populations of Drosophila melanogaster that have diverged from a common ancestral population as a result of a variety of definedExpand
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Selection on stress resistance increases longevity in Drosophila melanogaster
Tests for the causal involvement of specific physiological mechanisms in the control of aging require evidence that these mechanisms can be used to increase longevity or reproductive lifespan.Expand
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DOES SELECTION FOR STRESS RESISTANCE LOWER METABOLIC RATE
Environmental stress reduces the fitness of organisms, and in this manner may shape species distribution and evolutionary change. Ecologists have long been interested in physiological mechanisms thatExpand
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