Elderberry bark lectins evolved to recognize Neu5Ac alpha2,6Gal/GalNAc sequence from a Gal/GalNAc binding lectin through the substitution of amino-acid residues critical for the binding to sialic…
- H. Kaku, Hiroki Kaneko, N. Shibuya
- Biology, ChemistryJournal of Biochemistry (Tokyo)
- 1 September 2007
Findings indicated that the replacement of the corresponding amino-acid residues in a putative Gal/GalNAc-specific ancestral lectin to these amino- acid residues generated the unique Neu5Acalpha2,6Gal/Gal NAc- specific elderberry lectins in the course of molecular evolution.
Non-toxic type 2 ribosome-inactivating proteins (RIPs) from Sambucus: occurrence, cellular and molecular activities and potential uses.
- T. Girbés, J. Ferreras, M. Gayoso
- Biology, ChemistryCellular and Molecular Biology
- 1 June 2003
Conjugation of nigrin b or ebulin 1 to either transferrin or monoclonal antibodies provided highly active conjugates targeting cancer, and these non-toxic type 2 RIPs are promising tools for cancer therapy.
High prevalence of haemosporidians in Reed Warbler Acrocephalus scirpaceus and Sedge Warbler Acrocephalus schoenobaenus in Spain
- M. Fernández, M. Rojo, P. Casanueva, S. Carrión, M. Á. Hernández, F. Campos
- BiologyJournal of Ornithology
- 2009
High prevalence of malaria parasites was found in Reed Warbler and Sedge Warbler, and the degree of infection reach 100% of the population that breed at the Reserve, suggesting good conditions for the development of dipteran vectors in this area.
Ebulin 1, a nontoxic novel type 2 ribosome-inactivating protein from Sambucus ebulus L. leaves.
- T. Girbés, L. Citores, M. Calonge
- Biology, ChemistryJournal of Biological Chemistry
- 25 August 1993
Distribution and properties of major ribosome-inactivating proteins (28 S rRNA N-glycosidases) of the plant Saponaria officinalis L. (Caryophyllaceae).
- J. Ferreras, L. Barbieri, F. Stirpe
- Biology, ChemistryBiochimica et Biophysica Acta
- 19 October 1993
Molecular characterization and systemic induction of single-chain ribosome-inactivating proteins (RIPs) in sugar beet (Beta vulgaris) leaves.
- Rosario Iglesias, Y. Pérez, T. Girbés
- BiologyJournal of Experimental Botany
- 1 June 2005
The external application of purified beetin to sugar leaves prevented infection by AMCV which supports the preliminary hypothesis that beetins could be involved in plant systemic acquired resistance subjected to induction by phytopathogens.
Effects of ribosome-inactivating proteins on Escherichia coli and Agrobacterium tumefaciens translation systems
- T. Girbés, L. Barbieri, F. Stirpe
- BiologyJournal of Bacteriology
- 1 October 1993
The effects of 30 type 1 and of 2 ribosome-inactivating proteins (RIPs) on Escherichia coli and Agrobacterium tumefaciens cell-free translation systems were compared with the effects on a rabbit reticulocyte translation system.
Isolation, cDNA cloning, biological properties, and carbohydrate binding specificity of sieboldin-b, a type II ribosome-inactivating protein from the bark of Japanese elderberry (Sambucus…
- M. Rojo, M. Yato, N. Shibuya
- Biology, ChemistryArchives of Biochemistry and Biophysics
- 15 April 1997
It is revealed that sieboldin-b binds to Gal/GalNAc, similar to ricin/abrin, in spite of its highly homologous structure with SSA, and the possible explanation for such diversity is discussed.
Cusativin, a new cytidine-specific ribonuclease accumulated in seeds of Cucumis sativus L.
Cusativin represents a new class of plant RNase and, as far as the authors are aware, is the first plant enzyme that shows cleavage specificity for cytidine under the denaturing conditions of RNA sequencing.
cDNA molecular cloning and seasonal accumulation of an ebulin l-related dimeric lectin of dwarf elder (Sambucus ebulus L) leaves.
- M. Rojo, L. Citores, F. Arias, J. Ferreras, P. Jiménez, T. Girbés
- BiologyInternational Journal of Biochemistry and Cell…
- 1 July 2003
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