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- Publications
- Influence
Chromosome and gene copy number variation allow major structural change between species and strains of Leishmania.
- M. Rogers, J. Hilley, +15 authors J. Mottram
- Biology, Medicine
- Genome research
- 1 December 2011
Leishmania parasites cause a spectrum of clinical pathology in humans ranging from disfiguring cutaneous lesions to fatal visceral leishmaniasis. We have generated a reference genome for Leishmania… Expand
Quantifying influenza virus diversity and transmission in humans
- L. Poon, Timothy Song, +15 authors E. Ghedin
- Biology, Medicine
- Nature Genetics
- 4 January 2016
Influenza A virus is characterized by high genetic diversity. However, most of what is known about influenza evolution has come from consensus sequences sampled at the epidemiological scale that only… Expand
The complete chloroplast genome of the chlorarachniophyte Bigelowiella natans: evidence for independent origins of chlorarachniophyte and euglenid secondary endosymbionts.
- M. Rogers, P. Gilson, V. Su, G. McFadden, P. Keeling
- Biology, Medicine
- Molecular biology and evolution
- 2007
Chlorarachniophytes are amoeboflagellate cercozoans that acquired a plastid by secondary endosymbiosis. Chlorarachniophytes are the last major group of algae for which there is no completely… Expand
Gene Replacement of Fructose-1,6-Bisphosphate Aldolase Supports the Hypothesis of a Single Photosynthetic Ancestor of Chromalveolates
- N. Patron, M. Rogers, P. Keeling
- Biology, Medicine
- Eukaryotic Cell
- 1 October 2004
ABSTRACT Plastids (photosynthetic organelles of plants and algae) are known to have spread between eukaryotic lineages by secondary endosymbiosis, that is, by the uptake of a eukaryotic alga by… Expand
Lateral gene transfer and the evolution of plastid-targeted proteins in the secondary plastid-containing alga Bigelowiella natans
- J. Archibald, M. Rogers, Michael Toop, K. Ishida, P. Keeling
- Biology, Medicine
- Proceedings of the National Academy of Sciences…
- 30 May 2003
Chlorarachniophytes are amoeboflagellate algae that acquired photosynthesis secondarily by engulfing a green alga and retaining its plastid (chloroplast). An important consequence of secondary… Expand
Genomic Confirmation of Hybridisation and Recent Inbreeding in a Vector-Isolated Leishmania Population
- M. Rogers, T. Downing, +7 authors D. Smith
- Biology, Medicine
- PLoS genetics
- 1 January 2014
Although asexual reproduction via clonal propagation has been proposed as the principal reproductive mechanism across parasitic protozoa of the Leishmania genus, sexual recombination has long been… Expand
Phase variation in tcpH modulates expression of the ToxR regulon in Vibrio cholerae
- P. A. Carroll, K. Tashima, M. Rogers, V. DiRita, S. Calderwood
- Biology, Medicine
- Molecular microbiology
- 1 September 1997
We evaluated a spontaneous mutant of Vibrio cholerae, which was avirulent in an infant mouse and had reduced expression of cholera toxin and TcpA in response to environmental signals. The toxR, toxS… Expand
The ancestral symbiont sensor kinase CSK links photosynthesis with gene expression in chloroplasts
- Sujith Puthiyaveetil, T. Kavanagh, +7 authors J. F. Allen
- Biology, Medicine
- Proceedings of the National Academy of Sciences
- 22 July 2008
We describe a novel, typically prokaryotic, sensor kinase in chloroplasts of green plants. The gene for this chloroplast sensor kinase (CSK) is found in cyanobacteria, prokaryotes from which… Expand
Safety, Clinical Response, and Microbiome Findings Following Fecal Microbiota Transplant in Children With Inflammatory Bowel Disease.
- A. Goyal, Andrew Yeh, +5 authors M. Morowitz
- Medicine
- Inflammatory bowel diseases
- 18 January 2018
Background
The role of fecal microbiota transplant (FMT) in the treatment of pediatric inflammatory bowel disease (IBD) is unknown. The aims of this study were to assess safety, clinical response,… Expand
Complex distribution of EFL and EF-1α proteins in the green algal lineage
- G. P. Noble, M. Rogers, P. Keeling
- Biology, Medicine
- BMC Evolutionary Biology
- 23 May 2007
BackgroundEFL (or elongation factor-like) is a member of the translation superfamily of GTPase proteins. It is restricted to eukaryotes, where it is found in a punctate distribution that is almost… Expand