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Tourette syndrome, associated conditions and the complexities of treatment.
- M. Robertson
- Psychology, MedicineBrain : a journal of neurology
- 1 March 2000
It is suggested that TS is heterogeneous from a variety of standpoints including clinical presentation and psychopathology, and thus neuropharmacological responses and possibly even aetiological and genetic mechanisms are possible.
An international perspective on Tourette syndrome: selected findings from 3500 individuals in 22 countries
- R. Freeman, D. Fast, L. Burd, J. Kerbeshian, M. Robertson, P. Sandor
- Psychology, MedicineDevelopmental medicine and child neurology
- 1 July 2000
A multisite, international database of 3500 individuals diagnosed with Tourette syndrome, with wide variation among sites, can be used as the entry point for further research when large samples are studied and generalizability of results is important.
Lifetime prevalence, age of risk, and genetic relationships of comorbid psychiatric disorders in Tourette syndrome.
It is confirmed that psychiatric comorbidities are common among individuals with TS, demonstrates that most comor bidities begin early in life, and indicates that certain comorbiities may be mediated by the presence of comorbrid OCD or ADHD.
Analysis of shared heritability in common disorders of the brain
It is demonstrated that, in the general population, the personality trait neuroticism is significantly correlated with almost every psychiatric disorder and migraine, and it is shown that both psychiatric and neurological disorders have robust correlations with cognitive and personality measures.
The prevalence and epidemiology of Gilles de la Tourette syndrome. Part 1: the epidemiological and prevalence studies.
- M. Robertson
- Psychology, MedicineJournal of psychosomatic research
- 1 November 2008
The Gilles de la Tourette Syndrome: the Current Status
- M. Robertson
- Psychology, MedicineBritish Journal of Psychiatry
- 1 February 1989
A review briefly considers early descriptions of GTS as well as current research, highlighting the areas of agreement and controversy.
Executive function in Tourette's syndrome and obsessive–compulsive disorder
Specific set-shifting deficits in the OCD group contrasted with their intact performance on other tests of executive function, such as planning and decision-making, and suggested only limited involvement of frontal lobe dysfunction, possibly consistent with OCD symptomatology.
The international prevalence, epidemiology, and clinical phenomenology of Tourette syndrome: a cross-cultural perspective.
A functional neuroanatomy of tics in Tourette syndrome.
Aberrant activity in the interrelated sensorimotor, language, executive, and paralimbic circuits identified in this study may account for the initiation and execution of diverse motor and vocal behaviors that characterize tics in TS, as well as for the urges that often accompany them.
Deep brain stimulation in 18 patients with severe Gilles de la Tourette syndrome refractory to treatment: the surgery and stimulation
- D. Servello, M. Porta, M. Sassi, A. Brambilla, M. Robertson
- Medicine, PsychologyJournal of Neurology, Neurosurgery, and…
- 10 September 2007
The results of this and previous DBS reports suggest that the CM–Pfc and ventralis oralis complex of the thalamus may be a good DBS target for GTS.