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Specification of an anterior neuroectoderm patterning by Frizzled8a-mediated Wnt8b signalling during late gastrulation in zebrafish.
TLDR
It is suggested that a gradient of Fz8a-mediated Wnt8b signalling may play crucial role in patterning the posterior diencephalon and midbrain regions in the late gastrula. Expand
Zath3, a neural basic helix-loop-helix gene, regulates early neurogenesis in the zebrafish.
TLDR
It is suggested that zath3 and ngn1 have partially overlapping roles in early neurogenesis, with a subtle reduction of motor and inter-neurons and an almost complete loss all cranial ganglia. Expand
Isolation and expression of Napor/CUG-BP2 in embryo development.
TLDR
The cloning and characterization of a zebrafish Napor that has a high sequence homology to human NAPOR protein is reported, suggesting the need for tight control of napor gene regulation during embryo development. Expand
Activation of the thyroid-stimulating hormone beta-subunit gene by LIM homeodomain transcription factor Lhx2.
TLDR
Multiple lines of evidence are provided consistent with a role for Lhx2 in modulating expression of the TSH beta-subunit gene. Expand
Cloning and expression analysis of a Parkinson's disease gene, uch-L1, and its promoter in zebrafish.
TLDR
Results suggest that uch-L1 may have an important role in the development of neuronal cells in early embryos as well as in the degeneration and disease of neurons cells in late adult brain. Expand
Novel vector systems optimized for injecting in vitro-synthesized mRNA into zebrafish embryos.
TLDR
A vector, pcGlobin2, optimized for zebrafish, and its derivative, pc globin2-GST, which contains three critical elements 15' and 3' zebra fish beta-globin UTRs, and a poly(A) tail for generating stable mRNAs and greatly improving translation efficiency. Expand
Gonadotropin-releasing hormone-induced stimulation of the rat secretogranin II promoter involves activation of CREB
TLDR
Evidence is offered that GnRH-induced activation of the SgII promoter in the alphaT3-1 cell line requires cAMP-dependent protein kinase activity and a functional CRE within the 5'-flanking region of the gene. Expand
Snx5, as a Mind bomb‐binding protein, is expressed in hematopoietic and endothelial precursor cells in zebrafish
TLDR
Sorting nexin 5 (Snx5) is identified as a novel interacting partner of Mind bomb and it is demonstrated that Snx5 colocalizes with Mind bomb in early endosomal compartments, suggesting thatsnx5 is important for Mind bomb trafficking. Expand
Nrdp1 governs differentiation of the melanocyte lineage via Erbb3b signaling in the zebrafish embryogenesis.
TLDR
It is proposed that Nrdp1 is associated with differentiation process of the melanocyte lineage by regulating Erbb3b, an Erbb signaling molecule along zebrafish embryogenesis. Expand
Anti-resorptive saurolactam exhibits in vitro anti-inflammatory activity via ERK-NF-kappaB signaling pathway.
TLDR
It is proposed that the in vitro anti-inflammatory activity of saurolactam is produced by blocking ERK/MAP kinase and NF-kappaB activation. Expand
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