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Genetically Determined Differences in Learning from Errors
Dopamine D2 receptor reduction seems to decrease sensitivity to negative action consequences, which may explain an increased risk of developing addictive behaviors in A1-allele carriers.
Memory Consolidation by Replay of Stimulus-Specific Neural Activity
It is shown in healthy human participants that stimulus-specific activation patterns can indeed be identified with MVPA, that these patterns reoccur spontaneously during postlearning resting periods and sleep, and that the frequency of reactivation predicts subsequent memory for individual items.
Inferring candidate genes for Attention Deficit Hyperactivity Disorder (ADHD) assessed by the World Health Organization Adult ADHD Self-Report Scale (ASRS)
The German version of the World Health Organization Adult Attention Deficit Hyperactivity Disorder (ADHD) Self-Report Scale (ASRS) is tested, which is a short screening instrument for use in the general population and provides evidence for the structural as well as for the external validity of the ASRS.
Association of the functional catechol-O-methyltransferase VAL158MET polymorphism with the personality trait of extraversion
Results showed a significant association between catechol-O-methyltransferase, extraversion and the subscale exploratory excitement of novelty seeking but not with the total novelty-seeking scale supporting the psychometric analyses of the personality scales.
COMT genetic variation affects fear processing: psychophysiological evidence.
The findings support prior genetic and neuroimaging associations of the COMT 158Met allele to affective psychopathology and alterations in neural systems for emotional arousal and regulation.
Frontostriatal Involvement in Task Switching Depends on Genetic Differences in D2 Receptor Density
It is suggested that individual differences in striatal D2 signaling in healthy humans modulate goal-directed gating to prefrontal cortex, thus leading toindividual differences in switching intentionally to newly relevant behaviors.
Dopamine DRD2 Polymorphism Alters Reversal Learning and Associated Neural Activity
Results suggest that a genetically driven reduction in DA D2 receptors leads to deficient feedback integration in RCZ, which was accompanied by impaired recruitment of the ventral striatum and the right lOFC during reversals, which might explain the behavioral differences between the genetic groups.