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Medicinal plants and antimicrobial activity.
The past, present and future of medicinal plants are analyzed, both as potential antimicrobial crude drugs as well as a source for natural compounds that act as new anti-infection agents.
An Update Review of Saffron and its Active Constituents
This paper reviews the literature on recent research on the chemical composition and pharmacological activities of saffron (Crocus sativus) and its active constituents, mainly as antitumoral,…
Screening methods for natural products with antimicrobial activity: a review of the literature.
All the various techniques are reviewed here and, in order to unify the different criteria and parameters, standard methods to study the antimicrobial activity of medicinal plants are proposed.
Structural considerations on the iridoids as anti-inflammatory agents.
The results allowed us to establish the relationship between the structure and anti-inflammatory activity on the basis of the different patterns of substitution, particularly hydroxylation, unsaturation, and acylation.
Assessment of the anti-inflammatory activity and free radical scavenger activity of tiliroside.
- A. Sala, M. Recio, +4 authors José Luis Rosí
- Chemistry, MedicineEuropean journal of pharmacology
- 7 February 2003
Three flavonoids, gnaphaliin, pinocembrin and tiliroside, isolated from Helichrysum italicum, were studied in vitro for their antioxidant and/or scavenger properties and in vivo in different models…
Cocoa Polyphenols and Their Potential Benefits for Human Health
- I. Anduj́ar, M. Recio, R. Giner, J. Ríos
- Biology, MedicineOxidative medicine and cellular longevity
- 24 October 2012
The phenolics from cocoa may protect against diseases in which oxidative stress is implicated as a causal or contributing factor, such as cancer, and have antiproliferative, antimutagenic, and chemoprotective effects in addition to their anticariogenic effects.
Shikonin reduces oedema induced by phorbol ester by interfering with IκBα degradation thus inhibiting translocation of NF‐κB to the nucleus
- I. Anduj́ar, M. Recio, T. Bacelli, R. Giner, J. Ríos
- Biology, MedicineBritish journal of pharmacology
- 1 May 2010
The effect of shikonin on ear oedema induced by 12‐O‐tetradecanoylphorbol‐13‐acetate (TPA) is studied, and the mechanisms through which shik onin might exert its topical anti‐inflammatory action are determined.
Interaction of dicaffeoylquinic derivatives with peroxynitrite and other reactive nitrogen species.
- A. Olmos, R. Giner, M. Recio, J. Ríos, R. Gil-Benso, S. Máñez
- Chemistry, MedicineArchives of biochemistry and biophysics
- 1 July 2008
The assayed phenolics exert varying degrees of protection against the chemical modifications induced by RNS depending not only on the hydroxyl pattern, but also on the presence of bicarbonate.
Pharmacological properties of shikonin - a review of literature since 2002.
The aim of this review is to provide an update of the new data published on shikonin, whose wide spectrum of pharmacological effects as well as pharmacokinetic properties and toxicity make it a highly interesting target molecule.
Inhibition of ulcerative colitis in mice after oral administration of a polyphenol-enriched cocoa extract is mediated by the inhibition of STAT1 and STAT3 phosphorylation in colon cells.
- I. Anduj́ar, M. Recio, +4 authors J. Ríos
- Chemistry, MedicineJournal of agricultural and food chemistry
- 31 May 2011
The inhibitory effect of PCE on acute UC induced by DSS in mice was attenuated by oral administration ofPCE obtained from cocoa, principally due to the inhibition of transcription factors STAT1 and STAT3 in intestinal cells, with NF-κB inhibition also being implicated.