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Analgesic effect of i.v. paracetamol: possible ceiling effect of paracetamol in postoperative pain
TLDR
The correlation between serum paracetamol concentrations and the analgesic effect was studied and it was found that low concentrations are more likely to cause pain than high concentrations.
Recommended use of morphine in neonates, infants and children based on a literature review: Part 2–Clinical use
TLDR
It can be considered safe to administer morphine to neonates, infants or children, but treatment must be adjusted according to analgesic effect and incidence of side effects.
Recommended use of morphine in neonates, infants and children based on a literature review: Part 1—Pharmacokinetics
TLDR
The English language literature has been reviewed in order to evaluate the present knowledge on morphine's metabolism and pharmacokinetics in children, and volume of distribution, seems to be regardless of age, while half‐life and clearance were found to be related to age.
Examination of acetaminophen for outpatient management of postoperative pain in children
TLDR
Suggested dose ranges of acetaminophen do not provide sufficient pain relief in children following tonsillectomy and further studies are required to determine, whether higher doses of acetamol or analgesics with different analgesic properties will lead to improved analgesia in childrenFollowing tonsilslectomy.
Effect of a local anesthetic lozenge in relief of symptoms in burning mouth syndrome.
TLDR
The results indicate that the bupivacaine lozenge offers a novel therapeutic modality to patients with BMS, although without alleviating effect on the associated symptoms, taste alterations, and xerostomia.
Tropisetron reduces postoperative vomiting in children undergoing tonsillectomy
TLDR
Intravenous tropisetron was significantly (P<0.001, chi‐squared) more effective than placebo in controlling the incidence and frequency of emesis during the first 24 h: vomiting was reduced from 89% to 46% and the mean number of vomits from 4.6 to 2.4.
Pain Assessment of Subcutaneous Injections
TLDR
The results show that increasing the volume from 0.5 to 1.0 mL increases the pain significantly, which should be considered when injection preparations for subcutaneous administration are formulated.
Postoperative pain in children: comparison between ratings of children and nurses.
TLDR
The relationship between children's ratings of their pain and the nurses' ratings of the children's pain in a Danish hospital was examined to indicate that the nurses are not good at interpreting the patients' pain.
Tropisetron plus dexamethasone is more effective than tropisetron alone for the prevention of postoperative nausea and vomiting in children undergoing tonsillectomy
TLDR
Trisetron plus dexamethasone is more effective than tropisetron alone in reducing the incidence of PONV following paediatric tonsillectomy and a significant reduction in nausea was observed.
Postoperative pain in Danish children: self-report measures of pain intensity.
TLDR
Danish children as well as American children are able to use the Oucher as a method to self-report pain intensity, according to the results of this study.
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