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Hydrodynamics of soft active matter
This review summarizes theoretical progress in the field of active matter, placing it in the context of recent experiments. This approach offers a unified framework for the mechanical and statistical… Expand
Nanoscale Organization of Multiple GPI-Anchored Proteins in Living Cell Membranes
Cholesterol and sphingolipid-enriched "rafts" have long been proposed as platforms for the sorting of specific membrane components including glycosyl-phosphatidylinositol-anchored proteins (GPI-APs),… Expand
Nanoclusters of GPI-Anchored Proteins Are Formed by Cortical Actin-Driven Activity
Several cell-surface lipid-tethered proteins exhibit a concentration-independent, cholesterol-sensitive organization of nanoscale clusters and monomers. To understand the mechanism of formation of… Expand
Active Remodeling of Cortical Actin Regulates Spatiotemporal Organization of Cell Surface Molecules
- K. Gowrishankar, S. Ghosh, Suvrajit Saha, C. Rumamol, S. Mayor, M. Rao
- Biology, Medicine
- 8 June 2012
Many lipid-tethered proteins and glycolipids exist as monomers and nanoclusters on the surface of living cells. The spatial distribution and dynamics of formation and breakup of nanoclusters does not… Expand
Rheology of active-particle suspensions.
- Y. Hatwalne, S. Ramaswamy, M. Rao, R. Simha
- Physics, Materials Science
- Physical review letters
- 26 August 2003
We study the interplay of activity, order, and flow through a set of coarse-grained equations governing the hydrodynamic velocity, concentration, and stress fields in a suspension of active,… Expand
Rafts: Scale‐Dependent, Active Lipid Organization at the Cell Surface
Rafts have been conceptualized as lateral heterogeneities in the organization of cholesterol and sphingolipids, endowed with sorting and signaling functions. In this review we critically examine… Expand
Transbilayer Lipid Interactions Mediate Nanoclustering of Lipid-Anchored Proteins
Understanding how functional lipid domains in live cell membranes are generated has posed a challenge. Here, we show that transbilayer interactions are necessary for the generation of… Expand
Actomyosin dynamics drive local membrane component organization in an in vitro active composite layer
- D. Köster, Kabir B Husain, +5 authors S. Mayor
- Biology, Medicine
- Proceedings of the National Academy of Sciences
- 29 February 2016
Significance This manuscript addresses the role of active processes in the spatial organization and dynamics of cell surface components. Using a reconstituted minimal system, we provide experimental… Expand
Active organization of membrane constituents in living cells.
A search for organizing principles underlying molecular patterning at the cell surface and its regulation over different scales is necessary. This is important for understanding how the cell builds… Expand
Effect of B cell stimulatory factor-1 (interleukin 4) on Fc epsilon and Fc gamma receptor expression on murine B lymphocytes and B cell lines.
Culture of murine splenic B cells with interleukin 4 (IL-4) caused the up-regulation of the lymphocyte Fc receptor for immunoglobulin E (IgE) (Fc epsilon R) over a similar dose range as required for… Expand