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Adult haemophagocytic syndrome
Haemophagocytic syndromes (haemophagocytic lymphohistiocytosis) have a wide range of causes, symptoms, and outcomes, but all lead to a hyperinflammatory response and organ damage--mainly reported inExpand
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Morbidity and Mortality in Systemic Lupus Erythematosus During a 10-Year Period: A Comparison of Early and Late Manifestations in a Cohort of 1,000 Patients
In the present study, we assessed the frequency and characteristics of the main causes of morbidity and mortality in systemic lupus erythematosus (SLE) during a 10-year period and compared theExpand
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Clinical efficacy and side effects of antimalarials in systemic lupus erythematosus: a systematic review
Background: Antimalarial drugs (AMs), chloroquine (CQ) and hydroxychloroquine (HCQ), are frequently withdrawn in patients with lupus with either severe or remitting disease. However, additionalExpand
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Autoimmune Diseases Induced by TNF-Targeted Therapies: Analysis of 233 Cases
Tumor necrosis factor (TNF)-targeted therapies are increasingly used for a rapidly expanding number of rheumatic and autoimmune diseases. With this use and longer follow-up periods of treatment,Expand
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EULAR Sjögren's Syndrome Patient Reported Index (ESSPRI): development of a consensus patient index for primary Sjögren's syndrome
Objectives To develop a score for assessment of patients' symptoms in primary Sjögren's syndrome (SS): the EULAR SS Patient Reported Index (ESSPRI). Methods Dryness, pain, somatic and mental fatigueExpand
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The clinical spectrum of IgG4-related disease.
IgG4-related disease (IgG4-RD) is an emerging immune-mediated disease with the capability of involving essentially any organ. The epidemiology of this disease has not been explored in detail. AExpand
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Catastrophic Antiphospholipid Syndrome: Clues to the Pathogenesis from a Series of 80 Patients
The antiphospholipid syndrome (APS), originally defined as the combination of venous or arterial thrombotic events, recurrent fetal loss, and, frequently, a moderate thrombocytopenia in associationExpand
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Primary Sjögren Syndrome in Spain: Clinical and Immunologic Expression in 1010 Patients
We conducted the current study to characterize the clinical presentation of primary Sjögren syndrome (SS) in a large cohort of Spanish patients and to determine whether epidemiologic, clinical, andExpand
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Interstitial lung disease induced or exacerbated by TNF-targeted therapies: analysis of 122 cases.
OBJECTIVES To analyze the clinical characteristics, outcomes, and patterns of association with the different biologic agents used in all reported cases of adult patients developing interstitial lungExpand
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Vasculitis in Systemic Lupus Erythematosus: Prevalence and Clinical Characteristics in 670 Patients
Abstract: We conducted the current study to determine the prevalence and clinical characteristics of vasculitis in a large series of patients with systemic lupus erythematosus (SLE), focusing on theExpand
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