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Effects of bacterially synthesized recombinant human granulocyte-macrophage colony-stimulating factor in patients with advanced malignancy.
STUDY OBJECTIVE To define the clinical and hematologic effects of subcutaneously administered bacterially synthesized recombinant human granulocyte-macrophage colony-stimulating factor (rhGM-CSF). … Expand
Endopeptidase 24.11 inhibition by SCH 42495 in essential hypertension.
The detailed integrated renal, hormonal, and hemodynamic effects of acute (first dose) and established (4 days) inhibition of endopeptidase 24.11 by SCH 42495 (200 mg, every 12 hours) were documented… Expand
SAFETY AND EFFICACY OF MOMETASONE FUROATE CREAM IN THE TREATMENT OF STEROID RESPONSIVE DERMATOSES
- J. Kelly, G. Cains, M. Rallings, S. Gilmore
- The Australasian journal of dermatology
- 1 August 1991
The safety and efficacy of once daily application of mometasone furoate cream 0.1% was determined by comparison with twice daily applications of betamethasone dipropionate cream 0.05% in a single… Expand
Phase-II study of recombinant alpha 2-interferon in advanced malignant melanoma.
Fifteen patients with metastatic malignant melanoma, including 10 who had not previously received systemic therapy, were treated with recombinant alpha2-interferon (IFN-alpha 2) in a dose of 20… Expand
Phase I study of intravenously administered bacterially synthesized granulocyte-macrophage colony-stimulating factor and comparison with subcutaneous administration.
A Phase I study of bacterially synthesized recombinant human granulocyte-macrophage colony-stimulating factor (rhGM-CSF) was undertaken in 21 patients with advanced malignancy or neutropenia.… Expand
Phase-II Study of Recombinant α2-Interferon in Advanced Malignant Melanoma
ABSTRACT Fifteen patients with metastatic malignant melanoma, including 10 who had not previously received systemic therapy, were treated with recombinant α2-interferon (IFN-α2) in a dose of 20… Expand
Cytokine priming of acute myeloid leukemia may produce a pulmonary syndrome when associated with a rapid increase in peripheral blood myeloblasts.
The use of granulocyte-macrophage colony-stimulating factor (GM-CSF) administered before or in combination with chemotherapy represents a new strategy in the treatment of acute myeloid leukemia… Expand
Comparative study on the effects of recombinant alpha-2 interferon on immune function in patients with disseminated melanoma.
- P. Hersey, A. Coates, +6 authors G. Milton
- Journal of biological response modifiers
- 1 June 1986
Fifteen patients with disseminated melanoma were treated by intravenous administration of recombinant alpha-2 interferon (rIFN-alpha 2) on 5 consecutive days every 2 weeks. Immunological studies on… Expand
Lack of efficacy of a short ex vivo incubation of human allogeneic donor marrow with recombinant human GM-CSF prior to its infusion into the recipient.
Ten patients with haematological malignancy receiving allogeneic transplants from donors other than HLA-identical siblings were prepared for marrow transplantation with antithymocyte globulin,… Expand