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- Publications
- Influence
Three-Step Model for Polarized Sorting of KIF17 into Dendrites
- M. Franker, M. R. Silva, +7 authors C. Hoogenraad
- Biology, Medicine
- Current Biology
- 11 July 2016
Kinesin and dynein motors drive bidirectional cargo transport along microtubules and have a critical role in polarized cargo trafficking in neurons [1, 2]. The kinesin-2 family protein KIF17 is a… Expand
Activity-Dependent Actin Remodeling at the Base of Dendritic Spines Promotes Microtubule Entry
- P. Schätzle, M. R. Silva, R. Tas, E. Katrukha, C. Hoogenraad
- Biology, Medicine
- Current Biology
- 9 July 2018
In neurons, microtubules form dense bundles and run along the length of axons and dendrites. Occasionally, dendritic microtubules can grow from the shaft directly into dendritic spines. Microtubules… Expand
Cytoskeletal mechanisms of synaptic cargo trafficking
- M. R. Silva
- Biology
- 22 May 2017
The brain is a complex organ, responsible for the most important tasks performed by humans and animals. Neurons are an extraordinary type of brain cells. Their particular shape, with dendrites and… Expand
Regression of EEG correlates from simultaneous fMRI signals in epilepsy
- A. C. Santa, M. R. Silva
- 2018
The complementary properties of the Electroencephalography (EEG) and the Blood Oxygen Level Dependent (BOLD)-Functional Magnetic Resonance Imaging (fMRI) techniques have been particularly important… Expand
Abstract 986: High content analysis of 2D and 3D oncology models for target and phenotypic drug discovery
- Servane Lachize, R. V. D. Bospoort, +7 authors S. Jain
- Biology
- 1 July 2019
Charles River (CR) has developed many disease-relevant cellular models to screen small molecules and genetic modifiers for target and phenotypic based drug discovery. Our expertise and portfolio in… Expand