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Three-Step Model for Polarized Sorting of KIF17 into Dendrites
Kinesin and dynein motors drive bidirectional cargo transport along microtubules and have a critical role in polarized cargo trafficking in neurons [1, 2]. The kinesin-2 family protein KIF17 is aExpand
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Activity-Dependent Actin Remodeling at the Base of Dendritic Spines Promotes Microtubule Entry
In neurons, microtubules form dense bundles and run along the length of axons and dendrites. Occasionally, dendritic microtubules can grow from the shaft directly into dendritic spines. MicrotubulesExpand
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And if it is Not What it Seems
Cytoskeletal mechanisms of synaptic cargo trafficking
The brain is a complex organ, responsible for the most important tasks performed by humans and animals. Neurons are an extraordinary type of brain cells. Their particular shape, with dendrites andExpand
Regression of EEG correlates from simultaneous fMRI signals in epilepsy
The complementary properties of the Electroencephalography (EEG) and the Blood Oxygen Level Dependent (BOLD)-Functional Magnetic Resonance Imaging (fMRI) techniques have been particularly importantExpand
Abstract 986: High content analysis of 2D and 3D oncology models for target and phenotypic drug discovery
Charles River (CR) has developed many disease-relevant cellular models to screen small molecules and genetic modifiers for target and phenotypic based drug discovery. Our expertise and portfolio inExpand