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Effect of isoprenaline chronic stimulation on APD restitution and ventricular arrhythmogenesis.
BACKGROUND Isoprenaline (ISO) acts through β-adrenergic receptors to increase the intracellular Ca(2+), which has effects on action potential duration (APD) restitution and arrhythmogenesis. Thus, weExpand
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Absence of Rgs5 prolongs cardiac repolarization and predisposes to ventricular tachyarrhythmia in mice.
  • M. Qin, H. Huang, +5 authors C. Huang
  • Medicine, Chemistry
  • Journal of molecular and cellular cardiology
  • 20 November 2012
The aim of this study was to elucidate the effects of regulator of G-protein signaling 5 (Rgs5), a negative regulator of G-protein-mediated signaling, on cardiac repolarization and arrhythmia inExpand
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Atrial Tachyarrhythmia in Rgs5-Null Mice
Aims The aim of this study was to elucidate the effects of regulator of G-protein signaling 5 (Rgs5), a negative regulator of G protein-mediated signaling, on atrial repolarization andExpand
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Effects of Endothelin-1 Chronic Stimulation on Electrical Restitution, Beat-to-beat Variability of Repolarization, and Ventricular Arrhythmogenesis
Abstract: Chronically elevated levels of endothelin-1 (ET-1) have been detected in several cardiovascular diseases. In this study, we investigated the chronic effects of ET-1 on theExpand
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Neural substrate of posterior left atrium: A novel modulation for inducibility and remodeling of atrial fibrillation in canine
Background The neural mechanism of posterior left atrium (PLA) for genesis of atrial fibrillation has not been completely elucidated. We sought to assess the contribution of PLA denervation on atrialExpand
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Potential Role of Regulator of G‐Protein Signaling 5 in the Protection of Vagal‐Related Bradycardia and Atrial Tachyarrhythmia
Background The regulator of G‐protein signaling 5 (Rgs5), which functions as the regulator of G‐protein‐coupled receptor (GPCR) including muscarinic receptors, has a potential effect on atrialExpand
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[Activating protein kinase C enhances ventricular action potential duration restitution and increase arrhythmia susceptibility in Langendorff-perfused rabbit hearts].
OBJECTIVE To determine effects of activating protein kinase C (PKC) on ventricular action potential duration restitution (APDR) and Burst stimulus induced arrhythmia in Langendorff-perfused rabbitExpand
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Heart FailureMean heart rate from 24-h Holter recordings predicts total mortality in heart failure patientsThe prognosis investigation in patients with chronic heart failure and pericardial
# Mean heart rate from 24-h Holter recordings predicts total mortality in heart failure patients {#article-title-2} Purpose To estimate electrophysiological indices derived from non-invasiveExpand
The Gender Pressure and gender Ideal of school Girls
In the environment of contemporary social culture as a whole, gender equality in the law and policy and gender prejudice because of market ecnomic are opposite in coexistence, which constructs theExpand
Type,Content and Form of Community Volunteer Service
So far Chinese community volunteer service has formed a relatively complete cover and service field, developed plentiful service types, content and format.Its service type is mainly almsgiving,Expand