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The epidemiology of multiple sclerosis in Europe
TLDR
Comparing epidemiological indices among European countries is a hard task and often leads only to approximate estimates, which represents a major methodological concern when evaluating the MS burden in Europe and when implementing specific cost‐of‐illness studies.
Cost of disorders of the brain in Europe 2010
Vascular Factors and Risk of Dementia: Design of the Three-City Study and Baseline Characteristics of the Study Population
Objective: To describe the baseline characteristics of the participants in the Three-City (3C) Study, a study aiming to evaluate the risk of dementia and cognitive impairment attributable to vascular
The worldwide prevalence of multiple sclerosis
Estimating the Cost of Epilepsy in Europe: A Review with Economic Modeling
TLDR
The cost of epilepsy in Europe was estimated using available epidemiologic, health economic, and international population statistics literature to estimate the number of epilepsy patients in Europe.
Environmental risk factors in multiple sclerosis
TLDR
While genetics shapes the overall population MS susceptibility, observed epidemiological patterns strongly suggest a role for the environment in disease initiation and modulation.
Definition and diagnostic criteria of sleep-related hypermotor epilepsy
TLDR
It was recommended that the name be changed to sleep-related hypermotor epilepsy (SHE), reflecting evidence that the attacks are associated with sleep rather than time of day, the seizures may arise from extrafrontal sites, and the motor aspects of the seizures are characteristic.
An extremes of outcome strategy provides evidence that multiple sclerosis severity is determined by alleles at the HLA-DRB1 locus
TLDR
It is concluded that HLA-DRB1*01, previously implicated in disease resistance, acts as an independent modifier of disease progression, suggesting that shared quantitative MHC-based mechanisms are common to both patients and emphasizing the central role of this region in pathogenesis.
Clinical characteristics of patients with familial amyotrophic lateral sclerosis carrying the pathogenic GGGGCC hexanucleotide repeat expansion of C9ORF72.
TLDR
The phenotype of amyotrophic lateral sclerosis cases carrying C9ORF72 hexanucleotide repeat expansions was described by providing a detailed clinical description of affected cases from representative multi-generational kindreds, and by analysing the age of onset, gender ratio and survival in a large cohort of patients with familial amyotroph lateral sclerosis.
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