• Publications
  • Influence
The epidemiology of multiple sclerosis in Europe
Multiple sclerosis (MS) is a chronic and potentially highly disabling disorder with considerable social impact and economic consequences. It is the major cause of non‐traumatic disability in youngExpand
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The worldwide prevalence of multiple sclerosis
Despite the wealth of epidemiological data deriving from the systematic studies of multiple sclerosis (MS) that have been carried out for over 70 years, any attempt at redefining the pattern of MSExpand
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Vascular Factors and Risk of Dementia: Design of the Three-City Study and Baseline Characteristics of the Study Population
Objective: To describe the baseline characteristics of the participants in the Three-City (3C) Study, a study aiming to evaluate the risk of dementia and cognitive impairment attributable to vascularExpand
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Estimating the Cost of Epilepsy in Europe: A Review with Economic Modeling
Purpose: Based on available epidemiologic, health economic, and international population statistics literature, the cost of epilepsy in Europe was estimated.
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Environmental risk factors in multiple sclerosis
Objectives –  Multiple sclerosis (MS) likely results from an interaction between genetic and exogenous factors. While genetics shapes the overall population MS susceptibility, observedExpand
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Definition and diagnostic criteria of sleep-related hypermotor epilepsy
The syndrome known as nocturnal frontal lobe epilepsy is recognized worldwide and has been studied in a wide range of clinical and scientific settings (epilepsy, sleep medicine, neurosurgery,Expand
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Clinical characteristics of patients with familial amyotrophic lateral sclerosis carrying the pathogenic GGGGCC hexanucleotide repeat expansion of C9ORF72.
A large hexanucleotide (GGGGCC) repeat expansion in the first intron of C9ORF72, a gene located on chromosome 9p21, has been recently reported to be responsible for ~40% of familial amyotrophicExpand
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An extremes of outcome strategy provides evidence that multiple sclerosis severity is determined by alleles at the HLA-DRB1 locus
Multiple sclerosis (MS) is a common inflammatory disease of the central nervous system unsurpassed for variability in disease outcome. A cohort of sporadic MS cases (n = 163), taken from oppositeExpand
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Variants within the immunoregulatory CBLB gene are associated with multiple sclerosis
A genome-wide association scan of ∼6.6 million genotyped or imputed variants in 882 Sardinian individuals with multiple sclerosis (cases) and 872 controls suggested association of CBLB gene variantsExpand
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The increasing incidence and prevalence of MS in a Sardinian province
Objective: To verify incidence rates and their temporal trend in a homogeneous, ethnically, and genetically distinct population of central Sardinia (the Nuoro province). Background: IntensiveExpand
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