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SCH57404, an antifungal agent possessing the rare sodaricin skeleton and a tricyclic sugar moiety.
In the course of screening microbial fermentations for potential pharmaceutical activity, the extract from an unidentified fungus (Schering culture number SCF1082A) was found to inhibit CandidaExpand
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A novel class of antitumor metabolites from the fungus Nattrassia Mangiferae
Abstract Sch 49210, Sch 53514 and Sch 53516 have been isolated from a fungal culture, and identified by analysis of 2D NMR data. Two diacetylation derivatives Sch 53515 and Sch 53517 have beenExpand
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Verongamine, a novel bromotyrosine-derived histamine H3-antagonist from the marine sponge Verongula gigantea.
The novel bromotyrosine derivative verongamine [1] has been isolated from the marine sponge Verongula gigantea. The isolation of verongamine was facilitated by employing histamine-H3 bioassay-guidedExpand
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Saponins from Collinsonia canadensis
Akeboside St b {1} and two new saponins named collinsonin and collinsonidin were isolated from the roots of Collinsonia canadensis. Of the basis of chemical and spectral studies, the structure ofExpand
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Chemokine receptor CCR-5 inhibitors produced by Chaetomium globosum.
Two novel chemokine receptor CCR-5 inhibitors, Sch 210971 (1) and Sch 210972 (2), were isolated from the fungal fermentation broth of Chaetomium globosum by normal- and reversed-phase HPLCExpand
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Extensive 1D, 2D NMR Spectra of Some [7.0]Metacyclophanes and X-ray Analysis of (±)-Myricanol
From the hexane extract of the bark of Myrica cerifera, the pentacyclic triterpenes taraxerol and myricadiol were isolated. The EtOH extract afforded the [7.0]metacyclophanes, (±)-myricanol (4), andExpand
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A novel class of platelet activating factor antagonists from Phoma sp.
Four novel platelet activating factor (PAF) antagonists, Sch 47918, Sch 49026, Sch 49027 and Sch 49028, were isolated from the fermentation broth of the fungal culture, Phoma sp. (ATCC 74077). TheExpand
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Sch 54445: a new polycyclic xanthone with highly potent antifungal activity produced by Actinoplanes sp.
A novel antifungal agent, Sch 54445, was isolated from the fermentation broth of an Actinoplanes species. Sch 54445 was identified as a polycyclic xanthone related to the albofungin family ofExpand
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Sch 47918: A novel PAF antagonist from the fungus Phoma sp
A novel platelet activating factor (PAF) antagonist, Sch 47918, was isolated from the fermentation broth of the fungus, Phoma sp. The structure of this compound was elucidated by spectroscopicExpand
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