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Randomized placebo-controlled trial of mitoxantrone in relapsing-remitting multiple sclerosis: 24-month clinical and MRI outcome
Abstract We designed a randomized, placebo-controlled, multicentre trial involving 51 relapsing-remitting multiple sclerosis patients to determine the clinical efficacy of mitoxantrone treatment overExpand
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The SITS-MOST registry
In September 2002 the European Medicines Evaluation Agency (EMEA) approved a licence for alteplase (rt-PA) in the treatment of ischaemic stroke within 3 h of symptom onset. One of the conditionsExpand
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Prevalence of non-dementing cognitive disturbances and their association with vascular risk factors in an elderly population
Abstract.To assess the prevalence of "Cognitive Impairment No Dementia" (CIND) and circumscribed memory impairment (CMI) and to evaluate their association with vascular risk factors and stroke, weExpand
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A prevalence study of multiple sclerosis in L'Aquila, Central Italy
We report the results of an epidemiologic study in the Municipality of L'Aquila, Abruzzo, Central Italy, undertaken to estimate the prevalence rate of Multiple Sclerosis (MS). On December 31, 1984,Expand
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Autonomic cardiovascular function and baroreflex sensitivity in patients with cervical dystonia receiving treatment with botulinum toxin type A
ObjectiveTo investigate possible changes in autonomic cardiovascular regulation and cardiopulmonary baroreflex sensitivity in patients with primary cervical dystonia receiving chronic treatment withExpand
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Transcranial Doppler evaluation of cerebral blood flow in patients with paroxysmal atrial fibrillation
Cerebral blood flow was measured by transcranial Dopplersonography (TCD) in 15 patients during and after an attack of paroxysmal atrial fibrillation. During the attack the mean flow velocity (MFV)Expand
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[Prevalence and control of hypertension in chronic hemodialysis patients: results of a single-centre clinical audit].
Hypertension (HTN) is very common in chronic hemodialysis patients, with a prevalence of 72%, a very poor control and an annual mortality of 23%. We report the results of a clinical audit onExpand
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Topiramate and cortical excitability in humans: a study with repetitive transcranial magnetic stimulation
Repetitive transcranial magnetic stimulation (rTMS) delivered at 5 Hz frequency and suprathreshold intensity progressively increases the size of muscle evoked potentials (MEPs) and the duration ofExpand
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Case report of adult-onset Allgrove syndrome
Allgrove syndrome is a rare autosomal recessive disorder characterised by childhood onset, alacrima, oesophageal achalasia, adrenocortical insufficiency, neurological and occasionally autonomicExpand
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Adsorption Dialysis: From Physical Principles to Clinical Applications
The uremic syndrome is characterized by the retention of various solutes that would normally be excreted by the kidneys. The substances that interact negatively with biologic functions are calledExpand
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