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Hepatoprotective activity of aloe vera gel against paracetamol induced hepatotoxicity in albino rats
Objectives: To study the hepatoprotective activity of aqueous extract of Aloe vera in paracetamol induced hepatotoxicity inalbino rats.Methods: Hepatotoxicity was induced with a single dose ofExpand
Serum Paraoxonase 1 Activity Status in Patients with Liver Disorders
TLDR
PON1 activity has decreased significantly in acute viral hepatitis, sepsis with multi organ failure and falciparum malaria patients. Expand
Relationship between free iron and glycated hemoglobin in uncontrolled type 2 diabetes patients associated with complications
TLDR
Poor glycemic control and increase in glycation of haemoglobin is contributing to the increase in free iron pool which is known to increase oxidant generation. Expand
Paraoxonase: Its antiatherogenic role in chronic renal failure
TLDR
Enhancement or maintenance of the PON1 activity may prevent development of CVDs and its consequences in patients on hemodialysis. Expand
Copper and ceruloplasmin levels in relation to total thiols and GST in type 2 diabetes mellitus patients
TLDR
Possible increase in copper mediated generation of ROS leading to increased consumption of available antioxidants in the body is indicated, indicating possible increase in Copper mediated generation in type 2 diabetes mellitus cases compared to healthy controls. Expand
Evaluation of diuretic activity of Amaranthus spinosus Linn. aqueous extract in Wistar rats.
TLDR
The study strongly suggests that the Amaranthus spinosus is acting as a thiazide like diuretic with carbonic anhydrase inhibitory activity which restates the claim as diUREtic herb in Siddha medicine. Expand
Urine protein thiols in chronic renal failure patients
TLDR
Proteinuria is the most common finding in chronic renal failure (CRF), and protein-bound thiols, the major antioxidants in the body, are decreased in CRF cases. Expand
Determination of oxidative stress markers and their importance in early diagnosis of uremia-related complications
TLDR
The significant increase in level of MDA, and the decrease in levels of protein thiols, CP, and copper in uremia patients when compared to controls, reconfirms the presence of stress in this patient population. Expand
Role of non-transferrin-bound iron in chronic renal failure and other disease conditions
TLDR
It has been proved that in uremia or chronic renal failure patients, on conservative management or on hemodialysis program or under many other disease conditions, free iron or non-transferrin bound iron does exist; it induces damage to the biomolecules, thereby enhancing the disease process. Expand
Paraoxonase activity in type 2 diabetes mellitus patients with and without complications
TLDR
Type 2 DM patients with complications have significantly decreased HDL-C levels and PON1 activity, possibly indicating their decreased biochemical roles in these patients. Expand
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