• Publications
  • Influence
Metformin improves healthspan and lifespan in mice
Metformin is a drug commonly prescribed to treat patients with type 2 diabetes. Here we show that long-term treatment with metformin (0.1% w/w in diet) starting at middle age extends healthspan andExpand
  • 698
  • 40
  • PDF
Insulin-like Growth Factors, Their Binding Proteins, and Prostate Cancer Risk: Analysis of Individual Patient Data from 12 Prospective Studies
Context Insulin-like growth factors (IGFs) and IGF binding proteins may be associated with some cancers. Contribution This reanalysis of individual patient data from 12 studies of the associationExpand
  • 298
  • 6
  • PDF
Conversations with Ulrich Beck
Introduction: Thinking Society Anew (John Urry). 1. Post modernity or the second modernity. 2. Individualisation. 3. Global risk society. 4. Labour society and regime of risk. 5. Cosmopolitan societyExpand
  • 174
  • 6
Memória, esquecimento, silêncio
Halbwach's concept of collective memory (whose most complete expression would be national memory) is the starting point used in exploring how different processes and actors intervene in theExpand
  • 182
  • 6
Synthetic lethality screens reveal RPS6 and MST1R as modifiers of insulin-like growth factor-1 receptor inhibitor activity in childhood sarcomas.
The insulin-like growth factor-1 receptor (IGF1R) is emerging as a promising therapeutic target in human cancers. In the high-risk childhood sarcomas Ewing family tumor and rhabdomyosarcoma,Expand
  • 58
  • 5
Metformin in chemotherapy-naive castration-resistant prostate cancer: a multicenter phase 2 trial (SAKK 08/09).
BACKGROUND There is evidence linking metformin to improved prostate cancer (PCa)-related outcomes. OBJECTIVE To evaluate treatment with metformin in patients with castration-resistant PCa (CRPC)Expand
  • 77
  • 4
  • PDF
: Printing Presses: History and Development from the Fifteenth Century to Modern Times
Following your need to always fulfil the inspiration to obtain everybody is now simple. Connecting to the internet is one of the short cuts to do. There are so many sources that offer and connect usExpand
  • 13
  • 4
  • PDF
Hopping transport in solids
Preface. 1. Hopping conduction in the critical regime approaching the metal-insulator transition (T.G. Castner). 2. Hopping in band tails far from equilibrium (D. Monroe). 3. Non-Ohmic microwaveExpand
  • 306
  • 3
The Electron Glass
1. Introduction 2. Disordered electronic systems 3. Basics of glasses 4. Equilibrium properties of the electron glass 5. DC conductivity 6. Other transport properties of electron glasses 7. GlassyExpand
  • 63
  • 3
  • PDF