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Transcriptional Profiles of the Human Pathogenic Fungus Paracoccidioides brasiliensis in Mycelium and Yeast Cells*
The overall transcriptome analysis provided information about sequences related to the cell cycle, stress response, drug resistance, and signal transduction pathways of the pathogen.
Transcriptome characterization of the dimorphic and pathogenic fungus Paracoccidioides brasiliensis by EST analysis
The goal was to identify genes expressed in the mycelium and yeast forms by EST sequencing in order to generate a partial map of the fungus transcriptome and identify some genes potentially involved in the dimorphic transition and drug resistance.
Comparison of stem cell properties of cells isolated from normal and inflamed dental pulps.
- L. O. Pereira, M. R. Rubini, R. Azevedo
- Biology, MedicineInternational endodontic journal
- 1 December 2012
The morphology, proliferation rate and differentiation potential of DPSC-I were similar to the observed in DPSC -N, thus demonstrating that the inflammatory process did not affect the stem cell properties that were assessed.
The impact of chromatin remodelling on cellulase expression in Trichoderma reesei
The regulation of xylanase and cellulase expression in T. reesei is not only restricted to the action of transcription factors but also related to changes in the chromatin packaging, both the applied condition and the presence of Xyr1 influence chromatin status.
A truncated form of the Carbon catabolite repressor 1 increases cellulase production in Trichoderma reesei
- T. M. Mello-de-Sousa, Rita Gorsche, A. Rassinger, M. Poças-Fonseca, R. Mach, A. Mach-Aigner
- BiologyBiotechnology for Biofuels
- 11 September 2014
The investigation of the expression of two genes encoding cellulases and the gene encoding their main transactivator revealed that the presence of the truncated form of CREI (CREI-96) contributes more to the Rut-C30 phenotype than a general loss of CREi-mediated carbon catabolite repression or the deletion of 29 genes encoded in the scaffold 15.
The Relation Between Promoter Chromatin Status, Xyr1 and Cellulase Ex-pression in Trichoderma reesei
- T. M. Mello-de-Sousa, A. Rassinger, C. Derntl, M. Poças-Fonseca, R. Mach, A. Mach-Aigner
- BiologyCurrent genomics
- 31 March 2016
The xyr1 regulatory sequence is a good target for promoter engineering aiming at the enhancement of cellulase production and is overall more acces-sible in a cre1-truncated background, no matter which carbon source is present.
Thermophilic molds: Biology and applications
- Bijender Singh, M. Poças-Fonseca, B. N. Johri, T. Satyanarayana
- Biology, EngineeringCritical reviews in microbiology
- 17 January 2016
The analysis of genomes of thermophilic molds reveals high G:C contents, shorter introns and intergenic regions with lesser repetitive sequences, and further confirms their ability to degrade agro-residues efficiently.
Cloning, characterization and heterologous expression of the first Penicillium echinulatum cellulase gene
- M. R. Rubini, A. Dillon, C. Kyaw, F. Faria, M. Poças-Fonseca, I. Silva-Pereira
- BiologyJournal of applied microbiology
- 1 April 2010
This work describes for the first time the isolation, cloning and expression of a P. echinulatum cellulase cDNA (Pe‐egl1) encoding a putative endoglucanase.
HDAC genes play distinct and redundant roles in Cryptococcus neoformans virulence
This study directly correlates the effects of Class I/II HDAC-mediated chromatin remodeling on the marked phenotypic plasticity and virulence potential of this microorganism and provides insights into regulatory mechanisms involved in virulence gene expression that are likely shared with other microbial pathogens.
Substrate-dependent differential expression of Humicola grisea var. thermoidea cellobiohydrolase genes.
- M. Poças-Fonseca, I. Silva-Pereira, B. B. Rocha, O. Azevedo M de
- Biology, EngineeringCanadian journal of microbiology
- 1 August 2000
Transcription of fungal cellulase genes may be affected by substrate induction, and Humicola grisea var.