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Is liver biopsy still needed in children with chronic viral hepatitis?
TLDR
The current status of the liver biopsy in the management of chronic viral hepatitis B and C in pediatric population is presented, including specific indications, complications, contraindications, problems, limitations, and alternative non-invasive methods. Expand
Novel serum biomarkers modified by the body mass index z-score for the detection of liver fibrosis and steatosis in children with chronic hepatitis C
TLDR
Including the BMI z-score in serum biomarker formulas enhances their diagnostic ability to detect significant fibrosis and steatosis, and B-AST may act as an effective alternative to liver biopsy. Expand
Hepatitis C infection among pregnant women in central Poland: Significance of epidemiological anamnesis and impact of screening tests to detect infection.
TLDR
Establishing HCV infection risk factors during the interview process is the most common indicator for serological testing; however, not all infected cases can be diagnosed in this manner. Expand
Liver steatosis in children with chronic hepatitis B and C
TLDR
Steatosis is a common finding in children with chronic viral hepatitis, associated with metabolic factors in CHB, whereas in patients with CHC, metabolic and viral factors may have a combined effect, leading to more advanced grades of steatosis inChildren with higher BMI z-scores. Expand
Clinical usefulness of new noninvasive serum biomarkers for the assessment of liver fibrosis and steatosis in children with chronic hepatitis C
TLDR
Novel serum markers modified by the body mass index z-score were proposed as a reliable noninvasive alternative for the detection of significant fibrosis and steatosis in children with chronic hepatitis C (CHC). Expand
Non-invasive evaluation of the liver disease severity in children with chronic viral hepatitis using FibroTest and ActiTest – comparison with histopathological assessment
TLDR
The FT and AT values poorly correlate with histopathological evaluation, and further studies on non-invasive methods to evaluate liver disease severity in children with chronic viral hepatitis are needed. Expand
Determinants of liver disease progression in children with chronic hepatitis C virus infection.
TLDR
Children with chronic hepatitis C presented with mild liver changes over a decade after the infection, irrespective of the mode of transmission, and longer duration of infection and a higher BMI z-score were associated with more severe fibrosis. Expand
The micro-elimination approach - a new way of tackling hepatitis C in paediatric population
TLDR
Difficulties in achieving timebound elimination targets of the World Health Organization's Global Strategy on viral hepatitis might be overcome through a novel micro-elimination approach that assumes to focus elimination efforts on high-risk and left behind populations, and therefore allows for quick, efficient targeting of treatment and prevention services. Expand
Pruritic, Bizarre Tracks- A Vacation Souvenir.
TLDR
The clinical findings of imported CLM in a teenager returning from a youth camp are reported to highlight the methods of prevention and control of this emerging infection in returning travelers. Expand
Fever in an 8-Month-Old Infant Following a Rat Bite
TLDR
The case described below is that of an 8-month-old infant boy who was diagnosed with rat-bite fever. Expand
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