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Antidepressant-like effect of the extract of Rosmarinus officinalis in mice: Involvement of the monoaminergic system
The results suggest that the antidepressant action of the extract of R. officinalis is mediated by an interaction with the monoaminergic system and that this plant should be further investigated as an alternative therapeutic approach for the treatment of depression. Expand
Flavonoids: prospective drug candidates.
The biological properties of flavonoids include antioxidant, anti-inflamatory, antitumoral, antiviral and antibacterial, as well as a direct cytoprotective effect on coronary and vascular systems, the pancreas and the liver, place them among the most attractive natural substances available to enrich the current therapy options. Expand
Analysis of the Antinociceptive Effect of the Flavonoid Myricitrin: Evidence for a Role of the l-Arginine-Nitric Oxide and Protein Kinase C Pathways
The results indicate that myricitrin produces pronounced antinociception against chemical and mechanical models of pain in rodents and seems to involve an interaction with nitric oxide-l-arginine and protein kinase C pathways. Expand
Antioxidant Activity and Total Phenolic Content of Some Brazilian Species
Abstract The antioxidant activity of extracts and fractions of six vegetal species from the Brazilian Atlantic Forest were determined. The total antioxidant activity was assessed based on theExpand
Acute effect of Bauhinia forficata on serum glucose levels in normal and alloxan-induced diabetic rats.
Treatment of normal and alloxan-induced diabetic rats with BF decreased glucose levels, while this fraction was devoid of hypoglycemic effect in glucose-fed hyperglycemic normal rats. Expand
Chemical composition and antimicrobial activity of Croton urucurana Baillon (Euphorbiaceae).
Acetyl aleuritolic acid exhibits the best minimum inhibitory concentration (MIC) against both Staphylococcus aureus and Salmonella typhimurium. Expand
Anti-inflammatory action of hydroalcoholic extract, dichloromethane fraction and steroid α-spinasterol from Polygala sabulosa in LPS-induced peritonitis in mice.
These findings support the widespread use of Polygala sabulosa in popular medicine and demonstrate that this plant has therapeutic potential for the development of phytomedicines with anti-inflammatory properties. Expand
Anti-inflammatory and antioxidant effects of Croton celtidifolius bark.
It is demonstrated that Croton celtidifolius bark has significant anti-inflammatory and antioxidant activity. Expand
Hypoglycemic effect and antioxidant potential of kaempferol-3,7-O-(alpha)-dirhamnoside from Bauhinia forficata leaves.
Investigation of the effects of kaempferol-3,7-O-(alpha)-dirhamnoside (kaempferitrin), a major flavonoid compound of the n-butanol fraction from Bauhiniaforficata leaves, on serum glucose levels, as well as its antioxidant potential, found a significant hypoglycemic effect in normal and in alloxan-induced diabetic rats. Expand
Flavonoids: cellular and molecular mechanism of action in glucose homeostasis.
The purpose of this review is to discuss the cellular and molecular mechanisms of action of flavonoids focusing on carbohydrate metabolism. The beneficial effects of flavonoids have been studied inExpand