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Pathophysiological Mechanisms of Renal Fibrosis: A Review of Animal Models and Therapeutic Strategies.
Chronic kidney disease (CKD) is a long-term condition in which the kidneys do not work correctly. It has a high prevalence and represents a serious hazard to human health and estimated to affects… Expand
Histology, bioenergetics and oxidative stress in mouse liver exposed to N-diethylnitrosamine.
BACKGROUND A mouse model in which N-diethylnitrosamine (DEN) induces Hepatocellular carcinoma (HCC) has histological and genetic resemblance to human tumours. MATERIAL AND METHODS Male ICR mice… Expand
Biomonitoring of heavy metals (Cd, Hg, and Pb) and metalloid (As) with the Portuguese common buzzard (Buteo buteo)
- Manuela Carneiro, B. Colaço, +7 authors S. Lavín
- Chemistry, Medicine
- Environmental Monitoring and Assessment
- 30 July 2014
The accumulation of heavy metals in the environment may have a wide range of health effects on animals and humans. Thus, in this study, the concentrations of arsenic (As), cadmium (Cd), lead (Pb),… Expand
Bladder cancer-induced skeletal muscle wasting: disclosing the role of mitochondria plasticity.
- A. Padrão, Paula Oliveira, +13 authors R. Ferreira
- Biology, Medicine
- The international journal of biochemistry & cell…
- 1 July 2013
Loss of skeletal muscle is a serious consequence of cancer as it leads to weakness and increased risk of death. To better understand the interplay between urothelial carcinoma and skeletal muscle… Expand
HPV16 induces a wasting syndrome in transgenic mice: Amelioration by dietary polyphenols via NF‐&kgr;B inhibition
&NA; Cancer patients often show a wasting syndrome for which there are little therapeutic options. Dietary polyphenols have been proposed for treating this syndrome, but their usefulness in cases… Expand
Meloxicam in the treatment of in vitro and in vivo models of urinary bladder cancer.
- R. Arantes-Rodrigues, R. Pinto-Leite, +7 authors Paula A. Oliveira
- Chemistry, Medicine
- Biomedicine & pharmacotherapy = Biomedecine…
- 1 May 2013
To assess the efficacy of meloxicam, a non-steroidal anti-inflammatory drug (NSAID), on three human urinary bladder-cancer cell lines (HT1376, T24 and 5637) and on mice urinary bladder cancer… Expand
The Effects of Long-Term Chaetomellic Acid A Administration on Renal Function and Oxidative Stress in a Rat Model of Renal Mass Reduction
- A. Nogueira, Francisco P Peixoto, +4 authors M. Pires
- BioMed research international
- 23 February 2017
Purpose. This study aimed to evaluate the effect of chronic treatment with chaetomellic acid A (CAA) on oxidative stress and renal function in a model of renal mass reduction. Methods. Male Wistar… Expand
A framework for designing backroom areas in grocery stores
Purpose The design of retail backroom storage areas has great impact on in-store operations, customer service level and on store life-cycle costs. Moreover, backroom storage in modern retail… Expand
Estimation of rat mammary tumor volume using caliper and ultrasonography measurements
Mammary tumors similar to those observed in women can be induced in rats by intraperitoneal administration of N-methyl-N-nitrosourea. Determining tumor volume is a useful and quantitative way to… Expand
Opisthorchis felineus in cat: case report
Opisthorchis felineus foi encontrado em um gato admitido no Hospital Veterinario da Universidade de Tras-os-Montes e Alto Douro. No momento de admissao, o animal apresentava-se em estado de choque,… Expand