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Pathophysiological Mechanisms of Renal Fibrosis: A Review of Animal Models and Therapeutic Strategies.
Chronic kidney disease (CKD) is a long-term condition in which the kidneys do not work correctly. It has a high prevalence and represents a serious hazard to human health and estimated to affectsExpand
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Histology, bioenergetics and oxidative stress in mouse liver exposed to N-diethylnitrosamine.
BACKGROUND A mouse model in which N-diethylnitrosamine (DEN) induces Hepatocellular carcinoma (HCC) has histological and genetic resemblance to human tumours. MATERIAL AND METHODS Male ICR miceExpand
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Biomonitoring of heavy metals (Cd, Hg, and Pb) and metalloid (As) with the Portuguese common buzzard (Buteo buteo)
The accumulation of heavy metals in the environment may have a wide range of health effects on animals and humans. Thus, in this study, the concentrations of arsenic (As), cadmium (Cd), lead (Pb),Expand
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Bladder cancer-induced skeletal muscle wasting: disclosing the role of mitochondria plasticity.
Loss of skeletal muscle is a serious consequence of cancer as it leads to weakness and increased risk of death. To better understand the interplay between urothelial carcinoma and skeletal muscleExpand
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HPV16 induces a wasting syndrome in transgenic mice: Amelioration by dietary polyphenols via NF‐&kgr;B inhibition
&NA; Cancer patients often show a wasting syndrome for which there are little therapeutic options. Dietary polyphenols have been proposed for treating this syndrome, but their usefulness in casesExpand
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Meloxicam in the treatment of in vitro and in vivo models of urinary bladder cancer.
To assess the efficacy of meloxicam, a non-steroidal anti-inflammatory drug (NSAID), on three human urinary bladder-cancer cell lines (HT1376, T24 and 5637) and on mice urinary bladder cancerExpand
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The Effects of Long-Term Chaetomellic Acid A Administration on Renal Function and Oxidative Stress in a Rat Model of Renal Mass Reduction
Purpose. This study aimed to evaluate the effect of chronic treatment with chaetomellic acid A (CAA) on oxidative stress and renal function in a model of renal mass reduction. Methods. Male WistarExpand
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A framework for designing backroom areas in grocery stores
Purpose The design of retail backroom storage areas has great impact on in-store operations, customer service level and on store life-cycle costs. Moreover, backroom storage in modern retailExpand
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Estimation of rat mammary tumor volume using caliper and ultrasonography measurements
Mammary tumors similar to those observed in women can be induced in rats by intraperitoneal administration of N-methyl-N-nitrosourea. Determining tumor volume is a useful and quantitative way toExpand
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Opisthorchis felineus in cat: case report
Opisthorchis felineus foi encontrado em um gato admitido no Hospital Veterinario da Universidade de Tras-os-Montes e Alto Douro. No momento de admissao, o animal apresentava-se em estado de choque,Expand
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