M. Pilgrim

Publications14
h-index5
Citations232
Highly Influential Citations9
Claim Author Page
Author pages are created from data sourced from our academic publisher partnerships and public sources.

Recommended Authors

  • C. Curcio
  • 416 Publications • 23,427 Citations
  • I. Lengyel
  • 132 Publications • 1,721 Citations
  • J. Messinger
  • 103 Publications • 3,003 Citations
  • K. Freund
  • 663 Publications • 23,038 Citations
  • Publications
  • Influence
Calcified nodules in retinal drusen are associated with disease progression in age-related macular degeneration
TLDR
It is demonstrated that progression to AMD was associated with increasing degeneration of the RPE overlying HIRD, and that using multimodal clinical imaging to determine the composition of macular calcifications may help to direct therapeutic strategies and outcome measures in AMD.
Subretinal Pigment Epithelial Deposition of Drusen Components Including Hydroxyapatite in a Primary Cell Culture Model
TLDR
The data suggest that sub-RPE deposit formation is initiated, and probably regulated, by the RPE, as well as the loss of permeability of the Bruch's membrane and choriocapillaris complex associated with age and early AMD.
On the origin of proteins in human drusen: The meet, greet and stick hypothesis
Electron-microscopic findings after transmyocardial laser revascularization in an acute ischemic pig model.
Mineralisation within human tooth cementum identified by secondary ion mass spectrometry
TLDR
It is concluded that although ToF-SIMS analysis holds great promise for increasing the knowledge of cementum composition, far more caution is required by researchers linking observed lines in this tissue to underlying causal life history mechanisms and explanations.
A mineralomic study of the retinal pigment epithelium-Bruch’s membrane complex in human eyes with age-related macular degeneration
Clinical and nano-analytical imaging identify calcified nodules as progression markers for age-related macular degeneration
High-resolution imaging and molecular analysis of sub-retinal pigment epithelial deposits associated with age-related macular degeneration
Life history parameters in acellular extrinsic fiber cementum microstructure
TLDR
A new methodological approach for cementum research is proposed, Time-of-Flight Secondary Ion Mass Spectrometry (ToF-SIMS), to measure degree and distribution of mineralization of cementum growth layers, and shows that Tof- SIMS can significantly increase the authors' knowledge of cementu composition and is therefore a powerful new tool for life history researchers.
A primary retinal pigment epithelial (RPE) cell culture model produces lipid- and hydroxyapatite-rich extracellular deposits characteristic of early stage age-related macular degeneration
...
1
2
...