M. Pfaller

Publications97
h-index33
Citations4,173
Highly Influential Citations155
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"White-opaque transition": a second high-frequency switching system in Candida albicans
TLDR
A second high-frequency switching system was identified in selected pathogenic strains in the dimorphic yeast Candida albicans, referred to as the "white-opaque transition," which appears to be a fundamental difference in cellular morphology.
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Application of CHROMagar Candida for rapid screening of clinical specimens for Candida albicans, Candida tropicalis, Candida krusei, and Candida (Torulopsis) glabrata
TLDR
CHROMagar Candida is a new differential culture medium that allows selective isolation of yeasts and simultaneously identifies colonies of Candida albicans, C. tropicalis, and C. krusei and promises to improve and streamline the work flow in the mycology and clinical microbiology laboratory.
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Wild-Type MIC Distributions and Epidemiological Cutoff Values for the Echinocandins and Candida spp
TLDR
These WT MIC distributions and ECVs will be useful in surveillance for emerging reduced echinocandin susceptibility among Candida spp.
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Frequency of Decreased Susceptibility and Resistance to Echinocandins among Fluconazole-Resistant Bloodstream Isolates of Candida glabrata
TLDR
These data document the broad emergence of coresistance over time to both azoles and echinocandins in clinical isolates of C. glabrata and suggest that the first-line treatment of bloodstream infections due to Candida glabRata is still the best option.
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Genotypic variation and slime production among blood and catheter isolates of Candida parapsilosis
TLDR
Moderate genotypic variation among clinical isolates of C. parapsilosis is indicated and the propensity of these isolates to form slime in glucose-containing solutions suggests that this phenotypic characteristic may contribute to the ability to adhere to plastic catheters and cause infections.
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Elucidating the Origins of Nosocomial Infections with Candida albicans by DNA Fingerprinting with the Complex Probe Ca3
TLDR
The results demonstrate that single, dominant endemic strains are not responsible for nosocomial BSIs in neonatal ICUs and surgical ICUs, and suggest that multiple endemic strains may be responsible for a significant number of cases.
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Comparative evaluation of alternative methods for broth dilution susceptibility testing of fluconazole against Candida albicans
TLDR
Results show excellent agreement among alternative methods for fluconazole susceptibility testing of flu Conazole with 119 clinical isolates of Candida albicans.
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Identification of Candida dubliniensis Based on Temperature and Utilization of Xylose and α-Methyl-d-Glucoside as Determined with the API 20C AUX and Vitek YBC Systems
TLDR
Clinical microbiology laboratories could use lack of growth at 45°C and a negative XYL test with either the API 20C AUX or Vitek yeast identification system to provide a presumptive identification of C. dubliniensis.
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In vitro activity of a Hos2 deacetylase inhibitor, MGCD290, in combination with echinocandins against echinocandin-resistant Candida species.
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Evaluation of two commercial systems for identification of coagulase-negative staphylococci to species level.
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