• Publications
  • Influence
Arm immobilization causes cortical plastic changes and locally decreases sleep slow wave activity
Sleep slow wave activity (SWA) is thought to reflect sleep need, increasing after wakefulness and decreasing after sleep. We showed recently that a learning task involving a circumscribed brainExpand
  • 483
  • 28
  • PDF
A direct demonstration of cortical LTP in humans: A combined TMS/EEG study
Repetitive transcranial magnetic stimulation (rTMS) is increasingly being used to promote cortical reorganization, under the assumption that it can induce long-term potentiation (LTP) of neuralExpand
  • 276
  • 25
Reduced sleep spindle activity in schizophrenia patients.
OBJECTIVE High-density EEG during sleep represents a powerful new tool to reveal potential abnormalities in rhythm-generating mechanisms while avoiding confounding factors associated with wakingExpand
  • 322
  • 24
  • PDF
Reduced capacity to sustain positive emotion in major depression reflects diminished maintenance of fronto-striatal brain activation
Anhedonia, the loss of pleasure or interest in previously rewarding stimuli, is a core feature of major depression. While theorists have argued that anhedonia reflects a reduced capacity toExpand
  • 344
  • 22
  • PDF
Triggering sleep slow waves by transcranial magnetic stimulation
During much of sleep, cortical neurons undergo near-synchronous slow oscillation cycles in membrane potential, which give rise to the largest spontaneous waves observed in the normalExpand
  • 365
  • 16
  • PDF
Thalamic dysfunction in schizophrenia suggested by whole-night deficits in slow and fast spindles.
OBJECTIVE Slow waves and sleep spindles are the two main oscillations occurring during non-REM sleep. While slow oscillations are primarily generated and modulated by the cortex, sleep spindles areExpand
  • 218
  • 15
Sleep-dependent improvement in visuomotor learning: a causal role for slow waves.
STUDY OBJECTIVES Sleep after learning often benefits memory consolidation, but the underlying mechanisms remain unclear. In previous studies, we found that learning a visuomotor task is followed byExpand
  • 195
  • 9
Reduced evoked gamma oscillations in the frontal cortex in schizophrenia patients: a TMS/EEG study.
OBJECTIVE Transcranial magnetic stimulation (TMS) combined with high-density electroencephalography (EEG) can be used to directly examine the properties of thalamocortical circuits in the brainExpand
  • 190
  • 9
The Site of a Motor Memory Shifts with Consolidation
The basis for the consolidation of memory is a controversial topic, particularly in the case of motor memory. One view is that motor memory is transferred, partially or completely, to a new locationExpand
  • 126
  • 9
  • PDF
Relationships between changes in sustained fronto-striatal connectivity and positive affect in major depression resulting from antidepressant treatment.
OBJECTIVE Deficits in positive affect and their neural bases have been associated with major depression. However, whether reductions in positive affect result solely from an overall reduction inExpand
  • 100
  • 8
  • PDF