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Hereditary ovarian cancer in Poland.
TLDR
The high frequency of BRCA1 mutations in Polish women with ovarian cancer supports the recommendation that all Polish womenwith ovarian cancer should be offered testing for genetic susceptibility, and that counseling services be made available to them and to their relatives. Expand
BRCA1 and BRCA2 mutation analysis in breast‐ovarian cancer families from northeastern Poland
TLDR
The results suggest the presence of two strong BRCA1 founder mutations in the Polish population – 5382insC (6 families) and 300T>G (Cys61Gly; 3 families) – and conclude that the Polishpopulation has a more dispersed BRCa mutation spectrum than had been earlier thought. Expand
Hereditary ovarian cancer in Poland
TLDR
The high frequency of BRCA1 mutations in Polish women with ovarian cancer supports the recommendation that all Polish womenwith ovarian cancer should be offered testing for genetic susceptibility, and that counseling services be made available to them and to their relatives. Expand
Prevalence and clinical correlations of BRCA1/BRCA2 unclassified variant carriers among unselected primary ovarian cancer cases - preliminary report.
TLDR
The most significant predictors for pathogenic or unclassified variant changes in BRCA1 in ovarian cancer patients were a younger age of onset and a history of hyperthyroidism and infertility. Expand
Combined analysis of P53 Arg72Pro, GSTM1 and GSTT1 gene polymorphisms as predisposing factors for non-small cell lung cancer (NSCLC) development
TLDR
The aim of this study was to establish the frequencies of the polymorphic Arg72Pro, GSTM1 and GSTT1 genotypes in Polish population and to assess the associated risk of NSCLC development. Expand
Influence of diethylenetriamine (DETA) and sodium nitroprusside (NaNP) on sister chromatid exchange frequency and cell kinetics in cultured human lymphocytes.
TLDR
Diethylenetriamine and Sodium Nitroprusside, the exogenous NO-generating compounds, were tested for their genotoxicity in human lymphocytes in vitro using the sister chromatid exchange (SCE) technique and both compounds displayed an inhibiting effect on cell kinetics. Expand
Free movement of persons between Switzerland and the European Union and state security
The paper presents the phases of introducing free movement of persons, common rules within civil aviation between the EU and Switzerland, and the Schengen Agreement. Analysing this based on theExpand
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