• Publications
  • Influence
Effects of the obese gene product on body weight regulation in ob/ob mice.
TLDR
The data suggest that the OB protein regulates body weight and fat deposition through effects on metabolism and appetite.
A unique metabolic syndrome causes obesity in the melanocortin-3 receptor-deficient mouse.
TLDR
To assess the role of the MC3-R in energy homeostasis, the majority of themc3r coding sequence was deleted from the mouse genome and found that homozygous null mc3r mice exhibit an exclusively metabolic syndrome.
Urocortin, corticotropin releasing factor-2 receptors and energy balance.
TLDR
The data suggest that the central CRF(2) receptor may primarily mediate the anorexic, but not the metabolic effects of CRF.
A Unique Metalolic Sysdrone Causes Obesity in the Melanocortin-3 Receptor-Deficient Mouse.
TLDR
To assess the role of the MC3-R in energy homeostasis, the majority of themc3r coding sequence was deleted from the mouse genome and found that homozygous null mc3r mice exhibit an exclusively metabolic syndrome.
Characteristics of BDNF-induced weight loss
Pharmacological evidence supporting a role for central corticotropin-releasing factor(2) receptors in behavioral, but not endocrine, response to environmental stress.
TLDR
The data suggest that the CRF(2) receptor plays a role in the behavioral, but not the hypothalamic-pituitary-adrenal axis, response to stress.
Role of corticotropin-releasing factor (CRF) receptors in the anorexic syndrome induced by CRF.
TLDR
Data support the hypothesis that the CRF(2) receptor mediates the appetite suppression induced by CRF and suggest that theCRF( 2) receptor could mediate the stress-like behaviors that accompany CRF-induced appetite suppression.
Intraventricular administration of BDNF increases neuropeptide expression in newborn rat brain
TLDR
The observed effects in vivo on neuropeptide expression in various brain regions by injecting BDNF into the cerebroventricle of newborn rats suggest that BDNF regulates the development of neuropeptic expression in the CNS in a plastic manner.
...
...