• Publications
  • Influence
The Aspergillus PacC zinc finger transcription factor mediates regulation of both acid‐ and alkaline‐expressed genes by ambient pH.
The pH regulation of gene expression in Aspergillus nidulans is mediated by pacC, whose 678 residue‐derived protein contains three putative Cys2His2 zinc fingers. Ten pacCc mutations mimicking growthExpand
  • 595
  • 59
Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus
Aspergillus fumigatus is exceptional among microorganisms in being both a primary and opportunistic pathogen as well as a major allergen. Its conidia production is prolific, and so human respiratoryExpand
  • 1,191
  • 53
  • PDF
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
In 2008 we published the first set of guidelines for standardizing research in autophagy. Since then, research on this topic has continued to accelerate, and many new scientists have entered theExpand
  • 2,889
  • 44
  • PDF
Sequencing of Aspergillus nidulans and comparative analysis with A. fumigatus and A. oryzae
The aspergilli comprise a diverse group of filamentous fungi spanning over 200 million years of evolution. Here we report the genome sequence of the model organism Aspergillus nidulans, and aExpand
  • 1,216
  • 35
  • PDF
Tracing the endocytic pathway of Aspergillus nidulans with FM4-64.
  • M. Peñalva
  • Biology, Medicine
  • Fungal genetics and biology : FG & B
  • 1 December 2005
Simple procedures using FM4-64 to follow membrane internalization and transport to the vacuolar system and endomembranes in Aspergillus nidulans are described. FM4-64 internalization is energy,Expand
  • 174
  • 28
The tip growth apparatus of Aspergillus nidulans.
Hyphal tip growth in fungi is important because of the economic and medical importance of fungi, and because it may be a useful model for polarized growth in other organisms. We have investigated theExpand
  • 251
  • 25
Ambient pH gene regulation in fungi: making connections.
Many fungi grow over a wide pH range and their gene expression is tailored to the environmental pH. In Aspergillus nidulans, the transcription factor PacC, an activator of genes expressed in alkalineExpand
  • 278
  • 24
Preferential localization of the endocytic internalization machinery to hyphal tips underlies polarization of the actin cytoskeleton in Aspergillus nidulans
AbpA, SlaB and AmpA, three demonstrated components of the endocytic internalization machinery, are strongly polarized in Aspergillus nidulans hyphae, forming a ring that embraces the hyphal tip,Expand
  • 148
  • 20
YPXL/I Is a Protein Interaction Motif Recognized by Aspergillus PalA and Its Human Homologue, AIP1/Alix
ABSTRACT The zinc finger transcription factor PacC undergoes two-step proteolytic activation in response to alkaline ambient pH. PalA is a component of the fungal ambient pH signal transductionExpand
  • 150
  • 16
Arrestin-related proteins mediate pH signaling in fungi.
Metazoan arrestins bind to seven-transmembrane (7TM) receptors to regulate function. Aspergillus nidulans PalF, a protein involved in the fungal ambient pH signaling pathway, contains arrestinExpand
  • 145
  • 15
  • PDF