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Intracellular pH and activation of sea urchin eggs after fertilisation
The intracellular pH of the sea urchin embryo increases 0.3 pH units between 1 and 4 min after fertilisation. The increase in pH is required for initiating development. The increase results from anExpand
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Fertilization acid release in Urechis eggs. I. The nature of the acid and the dependence of acid release and egg activation on external pH.
The amount of fertilization acid produced by eggs of Urechis caupo , monitored by automatically back-titrating egg suspensions with base, depends linearly on the pH of the seawater. Above pH 7.0, atExpand
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Calcium influx following fertilization of Urechis caupo eggs.
Abstract Measurements of 45 Ca flux into and out of Urechis eggs indicate that, during the first 10 min after insemination, the eggs take up 0.24 pmole of Ca/egg. Total egg Ca measured by atomicExpand
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The polyspermy block in eggs of Urechis caupo. Evidence for a "rapid" block.
  • M. Paul
  • Biology, Medicine
  • Experimental cell research
  • 1975
Abstract Experiments have established the presence and time course of a polyspermy block in eggs of the echiuroid worm Urechis caupo. At various times after an initial insemination the eggs wereExpand
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Fertilization acid of sea urchin eggs is not a consequence of cortical granule exocytosis.
Sea urchin eggs treated with 10 mM NHC1 release a "fertilization acid" although cortical granule exocytosis does not take place. If the eggs are inseminated following ammonia activation, the corticalExpand
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Cytochalasin B inhibits sperm penetration into eggs of Urechis caupo (Echiura).
Abstract Cytochalasin B inhibits the penetration of sperm nuclei into Urechis eggs without inhibiting sperm-induced egg activation. The acrosome reaction appears normal, and plasma membranes of theExpand
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Release of acid and changes in light-scattering properties following fertilization of Urechis caupo eggs.
  • M. Paul
  • Biology, Medicine
  • Developmental biology
  • 1 April 1975
Abstract The release of a fertilization acid, monitored by measuring the pH of egg suspensions, begins within 10 sec of insemination of Urechis caupo eggs. This is 4 min before the vitelline layerExpand
  • 71
Uptake of Ca2+ is one of the earliest responses to fertilization of sea urchin eggs.
Sea urchin eggs take up Ca for 10 min following insemination (determined as uptake of 45Ca from the SW (3)). Although 90% of this uptake occurs after the beginning of the cortical reaction and mayExpand
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Formation of fertilization acid by sea urchin eggs does not require specific cations.
  • M. Paul, D. Epel
  • Biology, Medicine
  • Experimental cell research
  • 1 August 1975
Abstract We have measured the release of fertilization acid from sea urchin eggs in specific cation-free media by activating the eggs with the calcium ionophore A23187. The fertilization acid isExpand
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Fertilization-associated light-scattering changes in eggs of the sea urchin Strongylocentrotus purpuratus.
  • M. Paul, D. Epel
  • Biology, Medicine
  • Experimental cell research
  • 1 April 1971
Abstract Two major light-scattering changes have been detected in sea urchin egg suspensions in the first 4 min after insemination. The kinetics of the initial light-scattering (l.s.) change, aExpand
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