M. Parr

Publications138
h-index27
Citations2,338
Highly Influential Citations75
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Analysis of non-hormonal nutritional supplements for anabolic-androgenic steroids - results of an international study.
TLDR
A broad-based investigation of the international nutritional supplement market was initiated to clarify the extent of this problem and found that most of the positive supplements showed anabolic androgenic steroid concentrations of 0.01 micro g/g up to 190 microG/g.
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Nutritional supplements cross-contaminated and faked with doping substances.
TLDR
Since 2002 new 'designer' steroids such as prostanozol, methasterone, androstatrienedione etc have been offered on the nutritional supplement market and also cross-contamination with these steroids are expected.
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Unexpected contribution of cytochrome P450 enzymes CYP11B2 and CYP21, as well as CYP3A4 in xenobiotic androgen elimination - insights from metandienone metabolism.
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Mass spectrometric identification and characterization of a new long-term metabolite of metandienone in human urine.
TLDR
A new metabolite generated from metandienone has been identified as 18-nor-17beta-hydroxymethyl,17alpha-methyl-androst-1,4,13-trien-3-one in excretion study urine samples providing a valuable tool for the long-term detection of metandiensone abuse by athletes in sports drug testing.
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Detection of the misuse of steroids in doping control
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Estrogen receptor beta is involved in skeletal muscle hypertrophy induced by the phytoecdysteroid ecdysterone.
TLDR
Results indicate that ERβ is involved in the mediation of the anabolic activity of the Ecdy, and provide new therapeutic perspectives for the treatment of muscle injuries, sarcopenia, and cachectic disease, but also imply that such a substance could be abused for doping purposes.
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Investigations of the microbial transformation of cortisol to prednisolone in urine samples
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Clenbuterol marketed as dietary supplement.
TLDR
The present case for the first time confirms the presence of clenbuterol in a dietary supplement and demonstrates the common problem with products on the supplement market, where non-licensed pharmaceuticals and doping substances are easily available.
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Development of criteria for the detection of adrenosterone administration by gas chromatography-mass spectrometry and gas chromatography-combustion-isotope ratio mass spectrometry for doping control.
TLDR
It is proposed that adrenosterone may function as an inhibitor of the 11beta-hydroxysteroid dehydrogenase type 1 enzyme (11beta-HSD1), which is primarily responsible for reactivation of cortisol from cortisone.
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Toxicological findings in suicides – frequency of antidepressant and antipsychotic substances
TLDR
Toxicological findings from cross-sectional studies provide insight into how often certain types of antidepressants and antipsychotics are associated with suicide.
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