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Nigrostriatal function in humans studied with positron emission tomography
The dopamine depletion that is characteristic of Parkinson's disease has been hypothesized to result from the combination of environmentally induced subclinical damage to the substantia nigra and theExpand
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Cold but not sympathomimetics activates human brown adipose tissue in vivo
As potential activators of brown adipose tissue (BAT), mild cold exposure and sympathomimetic drugs have been considered as treatments for obesity and diabetes, but whether they activate the sameExpand
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Imaging of Inflamed and Vulnerable Plaque in Coronary Arteries with 18F-FDG PET/CT in Patients with Suppression of Myocardial Uptake Using a Low-Carbohydrate, High-Fat Preparation
PET/CT imaging with 18F-FDG has been used to detect inflammation in carotid and aortic plaque; its use in detecting coronary plaque has been limited by avid 18F-FDG uptake by the myocardium. WeExpand
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A critical examination of the results from the Harvard-MIT NCT program phase I clinical trial of neutron capture therapy for intracranial disease
SummaryA phase I trial was designed to evaluate normal tissue tolerance to neutron capture therapy (NCT); tumor response was also followed as a secondary endpoint. Between July 1996 and May 1999, 24Expand
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Regulation of Lateral Hypothalamic Orexin Activity by Local GABAergic Neurons
Orexin (also known as hypocretin) neurons are considered a key component of the ascending arousal system. They are active during wakefulness, at which time they drive and maintain arousal, and areExpand
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Spot scanning proton therapy for malignancies of the base of skull: treatment planning, acute toxicities, and preliminary clinical outcomes.
PURPOSE To describe treatment planning techniques and early clinical outcomes in patients treated with spot scanning proton therapy for chordoma or chondrosarcoma of the skull base. METHODS ANDExpand
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Measurement of Human Brown Adipose Tissue Volume and Activity Using Anatomic MR Imaging and Functional MR Imaging
The aim of this study was to assess the volume and function of human brown adipose tissue (BAT) in vivo using MR imaging. Methods: BAT volumes under thermoneutral conditions in the cervical areasExpand
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Extravazation of therapeutic yttrium-90-ibritumomab tiuxetan (zevalin): a case report.
The occurrence of radiation necrosis to the extravasation of therapeutic radionuclide-yttrium-90-ibritumomab tiuxetan-is described, as well as the subsequent steps taken to both address theExpand
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Dosimetry and adequacy of CT-based attenuation correction for pediatric PET: phantom study.
PURPOSE To evaluate the dose from the computed tomographic (CT) portion of positron emission tomography (PET)/CT to determine minimum CT acquisition parameters that provide adequate attenuationExpand
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Annihilation density distribution calculations for medically important positron emitters
The effect of positron range on the image-plane resolution of tomographic images is evaluated through calculations based on a model which employs beta-decay energy spectra and an empirical range formula. Expand
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