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Metabolic Syndrome, Chronic Kidney, and Cardiovascular Diseases: Role of Adipokines
- M. Tesauro, M. P. Canale, +4 authors C. Cardillo
- Cardiology research and practice
- 7 March 2011
Obesity and MetS affect renal physiology and metabolism through mechanisms which include altered levels of adipokines such as leptin and adiponectin, oxidative stress, and inflammation, which will help in designing more effective treatments aimed to protect both renal and cardiovascular systems. Expand
Obesity-Related Metabolic Syndrome: Mechanisms of Sympathetic Overactivity
- M. P. Canale, S. Manca di Villahermosa, +4 authors N. Di Daniele
- International journal of endocrinology
- 31 October 2013
Current understanding of some mechanisms through which sympathetic overactivity may be interlaced to the metabolic syndrome is focused on, with particular regard to the role of insulin resistance and of some adipokines. Expand
Role of transesophageal echocardiography in assessing diastolic dysfunction in a large clinical practice: a 9-year experience.
Two-dimensional and Doppler TEE with respiratory monitoring is useful in categorizing patients with impaired diastolic function, primarily into those with restrictive physiologic features or constrictive pericarditis. Expand
Diagnostic specificity of serum chromogranin-A for pheochromocytoma in patients with renal dysfunction.
Results show that serum CgA has poor diagnostic specificity in the diagnosis of pheochromocytoma when renal function is impaired, and combining C gA with plasma catecholamines provides a lower sensitivity, but excellent specificity, accuracy, and positive predictive value. Expand
Coronary artery calcifications predict long term cardiovascular events in non diabetic Caucasian hemodialysis patients
A full cost-benefit analysis is however necessary to justify a widespread use of cardiac multi-layer spiral computed tomography in clinical practice, as serum Parathyroid hormone levels were associated to a lower survival. Expand
Sulbactam/ampicillin versus cefotetan in the treatment of obstetric and gynecologic infections
- S. Scalambrino, C. Mangioni, +7 authors M. P. Canale
- Supplement to International journal of gynecology…
In an open, randomized clinical study, the safety and efficacy of sulbactam/ampicillin was compared to that of cefotetan in 95 hospital patients with gynecologic or obstetric infections and all patients were evaluated as cured. Expand
Soluble ST2 is a biomarker for cardiovascular mortality related to abnormal glucose metabolism in high-risk subjects
High circulating level of sST2 is associated to increased CVD mortality and markers of metabolic dysfunction in subjects with atherosclerotic disease. Expand
Preoperative Embolization Reduces the Risk of Cathecolamines Release at the Time of Surgical Excision of Large Pelvic Extra-Adrenal Sympathetic Paraganglioma
- N. Di Daniele, M. P. Canale, +5 authors G. Milito
- Case reports in endocrinology
- 4 September 2012
Preoperative embolization is a useful and safe procedure which may reduce the risk of catecholamines release at the time of surgical excision in large pelvic extra-adrenal sympathetic paraganglioma. Expand
Low Molecular Weight Adiponectin Increases the Mortality Risk in Very Old Patients
The hypothesis that high levels of Low Molecular Weight adiponectin are a biomarker for mortality risk in very old patients is supported and the association between high serum adiponECTin levels and increased mortality rate in elderly is suggested to be contingent to an unbalanced circulating levels of adip onectin isoforms. Expand
[Endoscopic polypectomy and adenoma-carcinoma sequence of the large intestine. Considerations on personal case series].
Overall, severe and moderate dysplasia was respectively observed in 6.7% and 23% of the adenomas, and location and sex did not seem to have a role in the malignant potential of adenomatous polyps. Expand