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- Publications
- Influence
Plasma membranes as heat stress sensors: from lipid-controlled molecular switches to therapeutic applications.
- Zsolt Török, T. Crul, +20 authors L. Vigh
- Biology, Medicine
- Biochimica et biophysica acta
- 1 June 2014
The classic heat shock (stress) response (HSR) was originally attributed to protein denaturation. However, heat shock protein (Hsp) induction occurs in many circumstances where no protein… Expand
Membrane-Lipid Therapy in Operation: The HSP Co-Inducer BGP-15 Activates Stress Signal Transduction Pathways by Remodeling Plasma Membrane Rafts
- Imre Gombos, T. Crul, +17 authors I. Horváth
- Medicine, Biology
- PloS one
- 12 December 2011
Aging and pathophysiological conditions are linked to membrane changes which modulate membrane-controlled molecular switches, causing dysregulated heat shock protein (HSP) expression. HSP co-inducer… Expand
The isoform-specific pathological effects of apoE4 in vivo are prevented by a fish oil (DHA) diet and are modified by cholesterol.
- Zehavit Kariv-Inbal, S. Yacobson, +6 authors D. Michaelson
- Biology, Medicine
- Journal of Alzheimer's disease : JAD
- 2012
Apolipoprotein E4 (apoE4) is the most prevalent genetic risk factor for Alzheimer's disease (AD). Epidemiological studies revealed that consumption of docosahexaenoic acid (DHA: 22 : 6 (ω3)), a major… Expand
Membrane lipid composition affects plant heat sensing and modulates Ca2+-dependent heat shock response
- Younousse Saidi, M. Péter, A. Finka, Cyril Cicekli, L. Vigh, P. Goloubinoff
- Biology, Medicine
- Plant signaling & behavior
- 1 December 2010
Understanding how plants sense and respond to heat stress is central to improve crop tolerance and productivity. Recent findings in Physcomitrella patensdemonstrated that the controlled passage of… Expand
Liquid chromatographic enantioseparation of beta-blocking agents with (1R,2R)-1,3-diacetoxy-1-(4-nitrophenyl)-2-propyl isothiocyanate as chiral derivatizing agent.
- M. Péter, Á. Gyéresi, F. Fülöp
- Chemistry, Medicine
- Journal of chromatography. A
- 2 March 2001
The applicability of (1R,2R)-1,3-diacetoxy-1-(4-nitrophenyl)-2-propyl isothiocyanate [(R,R)-DANI] as a recently developed chiral derivatizing agent for the enantioseparation of a series of… Expand
Atypical transcriptional regulation and role of a new toxin-antitoxin-like module and its effect on the lipid composition of Bradyrhizobium japonicum.
- Paul S Miclea, M. Péter, +5 authors I. Dusha
- Biology, Medicine
- Molecular plant-microbe interactions : MPMI
- 5 April 2010
A toxin-antitoxin (TA)-like system (designated as bat/bto genes) was identified in Bradyrhizobium japonicum, based on sequence homology and similarities in organization and size to known TA systems.… Expand
Docosahexaenoic Acid Reduces Amyloid β Production via Multiple Pleiotropic Mechanisms*
- M. Grimm, J. Kuchenbecker, +11 authors T. Hartmann
- Biology, Medicine
- The Journal of Biological Chemistry
- 15 February 2011
Alzheimer disease is characterized by accumulation of the β-amyloid peptide (Aβ) generated by β- and γ-secretase processing of the amyloid precursor protein (APP). The intake of the polyunsaturated… Expand
Lipidomics reveals membrane lipid remodelling and release of potential lipid mediators during early stress responses in a murine melanoma cell line.
- G. Balogh, M. Péter, +8 authors L. Vigh
- Biology, Medicine
- Biochimica et biophysica acta
- 1 September 2010
Membranes are known to respond rapidly to various environmental perturbations by changing their composition and microdomain organization. In previous work we showed that a membrane fluidizer benzyl… Expand
Heat Stress Causes Spatially-Distinct Membrane Re-Modelling in K562 Leukemia Cells
- G. Balogh, G. Maulucci, +10 authors L. Vigh
- Chemistry, Medicine
- PloS one
- 16 June 2011
Cellular membranes respond rapidly to various environmental perturbations. Previously we showed that modulations in membrane fluidity achieved by heat stress (HS) resulted in pronounced membrane… Expand
Comparison of column performances in direct high-performance liquid chromatographic enantioseparation of 1- or 3-methyl-substituted tetrahydroisoquinoline analogs. Application of direct and indirect…
The enantioseparability of 1- or 3-methyl-substituted tetrahydroisoquinolines was investigated by direct and indirect high-performance liquid chromatography. Alpha- and beta-cyclodextrin-,… Expand