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Microarray analysis identifies versican and CD9 as potent prognostic markers in gastric gastrointestinal stromal tumors
Genetic or epigenetic changes other than c‐kit play important roles in the metastatic process of gastric GIST, and versican and CD9 are potential prognostic markers in gastrics GIST.
The role of circulating IL‐8 and VEGF protein in the progression of gastric cancer
- H. Konno, M. Ohta, Megumi Baba, Shohachi Suzuki, Satosi Nakamura
- MedicineCancer science
- 1 August 2003
The measurement of IL‐8 levels in drainage veins of GC patients may reflect production mainly by the primary lesion and is valuable as an indicator of risk for recurrent disease.
TSU68 prevents liver metastasis of colon cancer xenografts by modulating the premetastatic niche.
The results suggest that the CXCL1/CXCR2 axis is important in cancer metastasis and that TSU68 may modulate the premetastatic niche in the target organ through suppression of the inflammatory response, which might be an alternative mechanism used by antiangiogenic agents.
Overexpression of Lysophosphatidylcholine Acyltransferase 1 and Concomitant Lipid Alterations in Gastric Cancer
- T. Uehara, H. Kikuchi, +11 authors H. Konno
- Biology, MedicineAnnals of Surgical Oncology
- 16 September 2016
Overexpressed LPCAT1 protein in gastric mucosa appears to play important roles in the tumorigenic process of gastric cancer by converting LPC to PC.
Mesenteric paraganglioma: Report of a case.
- Takeshi Fujita, K. Kamiya, +7 authors H. Konno
- MedicineWorld journal of gastrointestinal surgery
- 27 March 2013
Mesenteric paraganglioma, as in this case, is extremely rare; only 11 cases have been reported in the literature and the clinical findings are discussed.
Prevention of liver metastasis of human colon cancer by selective matrix metalloproteinase inhibitor MMI-166.
Near-infrared multichannel Raman spectroscopy with a 1064 nm excitation wavelength for ex vivo diagnosis of gastric cancer.
Anti‐VEGF antibody therapy induces tumor hypoxia and stanniocalcin 2 expression and potentiates growth of human colon cancer xenografts
- Shinichiro Miyazaki, H. Kikuchi, +10 authors H. Konno
- MedicineInternational journal of cancer
- 15 July 2014
In vivo serial transplantation of TK‐4 revealed that long‐term administration of anti‐VEGF antibodies increased the tumorigenicity of colon cancers and accelerated tumor growth when transplanted into secondary recipient mice, providing a potential molecular explanation for the limited clinical effectiveness of anti-VEGF antibody treatment.
Gastrojejunocolic Fistula After Gastrectomy with Billroth II Reconstruction: Report of a Case
Gastrojejunocolic fistula should be recognized as one of the late severe complications observed after a gastrectomy with Billroth II reconstruction, since this disease may occur even 20 years after the first operation for peptic ulcer.