M. Ochi

Publications761
h-index75
Citations22,037
Highly Influential Citations720
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Expression of microRNA-146 in rheumatoid arthritis synovial tissue.
TLDR
This study shows that miR-146 is expressed in RA synovial tissue and that its expression is induced by stimulation with TNFalpha and IL-1beta and further studies are required to elucidate the function of miR -146 in these tissues.
MicroRNA-146a expresses in interleukin-17 producing T cells in rheumatoid arthritis patients
TLDR
Results indicated that miR-146a was associated with IL-17 expression in the PBMC and synovium in RA patients, and there is the possibility thatMiR- 146a participates in the IL- 17 expression.
Expression of MicroRNA-146a in osteoarthritis cartilage.
TLDR
This study shows that miR-146 is intensely expressed in low-grade OA cartilage and that its expression is induced by stimulation of IL-1beta, which might play a role in OAcartilage pathogenesis.
Diagnosis of a tear of the tibiofibular syndesmosis. The role of arthroscopy of the ankle.
TLDR
It is suggested that arthroscopy of the ankle is indispensable for the accurate diagnosis of a tear of the tibiofibular syndesmosis.
Cryotherapy influences joint laxity and position sense of the healthy knee joint.
TLDR
Cooling for 15 minutes makes the knee joint stiffer and lessens the sensitivity of the position sense and these findings may be significant and should be taken into account for therapeutic programs that involve exercise immediately after a period of cooling.
Mesenchymal‐stem‐cell‐derived exosomes accelerate skeletal muscle regeneration
Mesenchymal Stem Cell‐Derived Exosomes Promote Fracture Healing in a Mouse Model
TLDR
Exosomes are a novel factor of MSC paracrine signaling with an important role in the tissue repair process and suggest that exosomes in CM facilitate the acceleration of fracture healing.
The inhibitory effect of microRNA-146a expression on bone destruction in collagen-induced arthritis.
TLDR
Findings indicate that expression of miR-146a inhibits osteoclastogenesis and that administration of double-stranded miR -146a prevents joint destruction in arthritic mice and has potential as a novel therapeutic target for bone destruction in RA.
Interobserver Reliability of the International Society of Arthroscopy, Knee Surgery and Orthopaedic Sports Medicine (ISAKOS) Classification of Meniscal Tears
TLDR
The ISAKOS classification of meniscal Tears provides sufficient interobserver reliability for pooling of data from international clinical trials designed to evaluate the outcomes of treatment for meniscal tears.
Acceleration of muscle regeneration by local injection of muscle-specific microRNAs in rat skeletal muscle injury model
TLDR
It is demonstrated that a local injection of double‐stranded miR-1, miR‐133 and 206 can accelerate muscle regeneration in a rat skeletal muscle injury model and could be a novel therapeutic strategy in the treatment of skeletal muscle injuries.
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