Ultrasensitive pheromone detection by mammalian vomeronasal neurons
This work uses a mouse VNO slice preparation to show that six putative pheromones evoke excitatory responses in single vomeronasal neurons, leading to action potential generation and elevated calcium entry, providing a basis for understanding chemical signals that regulate mammalian communication and sexual behaviour.
Synthetic pheromones that promote inter-male aggression in mice.
- M. Novotny, S. Harvey, B. Jemioło, J. Alberts
- Biology, PsychologyProceedings of the National Academy of Sciences…
- 1 April 1985
Two volatile constituents of male mouse urine, dehydro-exo-brevicomin and 2-(sec-butyl)-dihydrothiazole, have been found active in bioassays of inter-male aggressive behavior and provoke fighting that is quantitatively and qualitatively comparable to that elicited by intact male urine.
Pheromones, binding proteins and receptor responses in rodents.
- M. Novotny
- BiologyBiochemical Society Transactions
- 1 February 2001
Structural identification of several pheromones in mice, rats and hamsters now makes it feasible to employ their synthetic analogues in probing olfactory neurons and in the study of various pherOMone-protein interactions in intimate detail.
Analytical Chemistry of Polycyclic Aromatic Compounds
Songbird chemosignals: volatile compounds in preen gland secretions vary among individuals, sexes, and populations.
- Danielle J Whittaker, H. Soini, J. Atwell, Craig Hollars, M. Novotny, E. Ketterson
- Biology, Environmental ScienceBehavioral Ecology
- 1 May 2010
It is suggested that songbird preen oil odors have the potential to function as chemosignals associated with mate recognition or reproductive isolation as well as significant sex and population differences in volatile profiles.
Seasonal Variation in Volatile Compound Profiles of Preen Gland Secretions of the Dark-eyed Junco (Junco hyemalis)
- H. Soini, S. Schrock, K. E. Bruce, D. Wiesler, E. Ketterson, M. Novotny
- Chemistry, MedicineJournal of Chemical Ecology
- 5 December 2006
Functionally, the large increase in linear alcohols in male and female preen oil during the breeding season may be an indication of altered lipid biosynthesis, which might signal reproductive readiness, and Linear alcohols might also facilitate junco odor blending with plant volatiles in the habitat to distract mammalian predators.
Comparison of the methods for profiling glycoprotein glycans--HUPO Human Disease Glycomics/Proteome Initiative multi-institutional study.
The results of this multi-institutional study indicate that MS-based analysis appears as the efficient method for identification and quantitation of oligosaccharides in glycomic studies and endorse the power of MS for glycopeptide characterization with high sensitivity in proteomic programs.
Positive identification of the puberty-accelerating pheromone of the house mouse: the volatile ligands associating with the major urinary protein
- M. Novotny, W. Ma, D. Wiesler, L. Žídek
- BiologyProceedings of the Royal Society of London…
- 7 October 1999
Five structurally diverse small ligands, all binding to the major urinary protein (MUP) of the male house mouse, show individually puberty-accelerating pheromonal activity in the recipient females, and now appear responsible for both sexual maturation and cycling in adult females.
Chemistry of male dominance in the house mouse,Mus domesticus
It is suggested that these compounds may play a wide-ranging role in the territorial marking behavior of male mice, and may be synonymous with the previously described aversion signal produced by dominant males.
Individual and gender fingerprints in human body odour
This is the first study on human axillary odour to sample a large number of subjects, and the findings are relevant to understanding the chemical nature of human odour, and efforts to design electronic sensors for biometric fingerprinting and disease diagnoses.