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Association between the efficacy of half-dose photodynamic therapy with indocyanine green angiography and optical coherence tomography findings in the treatment of central serous chorioretinopathy.
The half-dose PDT success rate in eyes with chronic CSC depends also on the distribution of fluid in the neuroepithelium, namely subretinal fluid or posterior retinal cystoid degeneration.
Combining macula clinical signs and patient characteristics for age-related macular degeneration diagnosis: a machine learning approach
Both black-box and white box methods performed well in identifying diagnoses of AMD and their decision pathways, and machine learning models developed through the proposed approach could be embedded into EHR to provide physicians with real time (interpretable) support.
OCCULT WITH NO CLASSIC CHOROIDAL NEOVASCULARIZATION SECONDARY TO AGE-RELATED MACULAR DEGENERATION TREATED BY INTRAVITREAL TRIAMCINOLONE AND PHOTODYNAMIC THERAPY WITH VERTEPORFIN
Improvement of best-corrected visual acuity and lack of fluorescein leakage suggest combination treatment with IVT and PDT for occult with no classic CNV merits further investigation.
Vascular endothelial growth factor-C secretion is increased by advanced glycation end-products: possible implication in ocular neovascularization
- A. Puddu, R. Sanguineti, A. Durante, M. Nicolò, G. Viviani
- Biology, MedicineMolecular vision
- 11 October 2012
The findings suggest that AGEs take part in the onset of retinal neovascularization, not only by modulating V EGF-A but also by increasing VEGF-C secretion.
Detection of tenascin-C in surgically excised choroidal neovascular membranes
- M. Nicolò, F. Piccolino, L. Zardi, A. Giovannini, C. Mariotti
- Biology, MedicineGraefe's Archive for Clinical and Experimental…
- 1 February 2000
The results support the concept that TN-C has a role in cell proliferation and neovascularization in humans, and may provide novel rationales for the development of pharmacologic therapies for neov vascular disorders, particularly CNV.
Ranibizumab for Visual Impairment due to Diabetic Macular Edema: Real-World Evidence in the Italian Population (PRIDE Study)
Ranibizumab was well-tolerated and improved/maintained VA in 40.2%–68.8% patients, with no differences in case of unilateral or bilateral pathology, and no difference in the VA outcomes and treatment exposure between unilateral/bilateral patients.
Retinal pigment epithelial tear following intravitreal injection of bevacizumab (Avastin).
This report describes the development of retinal pigment epithelium tear after intravitreal bevacizumab injection and which subtypes of lesions are most susceptible to this potential devastating visual complication.
Multiple Bilateral Choroidal Metastatic Tumors from a Small-Cell Neuroendocrine Carcinoma of Unknown Primary Site
- M. Nicolò, F. Piccolino, D. Ghiglione, G. Nicolò, G. Calabria
- MedicineEuropean journal of ophthalmology
- 1 January 2005
The case of a 30-years-old white female who developed multiple and bilateral choroidal tumors from a poorly differentiated small cell neuroendocrine carcinoma of unknown primary is presented and described together with a review of the literature.
Eales disease associated with serpiginous choroiditis.
- A. Fung, M. Nicolò, S. Yzer, C. Traverso, L. Yannuzzi
- MedicineArchives of ophthalmology
- 1 November 2012
Although tuberculous infection and/or hypersensitivity has been associated with both Eales disease and serpiginous choroiditis, the evidence remains inconclusive.
Half-fluence versus half-dose photodynamic therapy in chronic central serous chorioretinopathy.
- M. Nicolò, C. Eandi, +4 authors F. Cardillo Piccolino
- MedicineAmerican journal of ophthalmology
- 1 May 2014
Half-dose PDT induced a more rapid reabsorption of the fluid, a more lasting effect, and equal safety with respect to half-fluence PDT.