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Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010
TLDR
The results for 1990 and 2010 supersede all previously published Global Burden of Disease results and highlight the importance of understanding local burden of disease and setting goals and targets for the post-2015 agenda taking such patterns into account. Expand
Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010
TLDR
Prevalence and severity of health loss were weakly correlated and age-specific prevalence of YLDs increased with age in all regions and has decreased slightly from 1990 to 2010, but population growth and ageing have increased YLD numbers and crude rates over the past two decades. Expand
Randomised trial of effect of alendronate on risk of fracture in women with existing vertebral fractures
TLDR
Among women with low bone mass and existing vertebral fractures, alendronate is well tolerated and substantially reduces the frequency of morphometric and clinical vertebra fractures, as well as other clinical fractures. Expand
Vertebral fracture assessment using a semiquantitative technique
TLDR
The semiquantitative approach can be applied reliably in vertebral fracture assessment when performed using well‐defined criteria, and this approach was compared with a quantitative morpho‐metric approach. Expand
Osteoarthritis: New Insights. Part 1: The Disease and Its Risk Factors
TLDR
This article is part 1 of a two-part summary of an NIH conference, Stepping Away with OA: Prevention of Onset, Progression, and Disability of Osteoarthritis, which brought together experts in osteoarth arthritis from diverse backgrounds and provided a multidisciplinary and comprehensive summary of recent advances in the prevention. Expand
Gait speed and survival in older adults.
TLDR
In this pooled analysis of individual data from 9 selected cohorts, gait speed was associated with survival in older adults and predicted survival was as accurate as predicted based on age, sex, use of mobility aids, and self-reported function. Expand
BMD at Multiple Sites and Risk of Fracture of Multiple Types: Long‐Term Results From the Study of Osteoporotic Fractures
TLDR
Almost all fracture types to be related to low BMD are found, and the overall proportion of fractures attributable toLow BMD is modest. Expand
A prospective study of physical activity and cognitive decline in elderly women: women who walk.
TLDR
Women with higher levels of baseline physical activity were less likely to develop cognitive decline and this finding supports the hypothesis that physical activity prevents cognitive decline in older community-dwelling women. Expand
The osteoarthritis initiative: report on the design rationale for the magnetic resonance imaging protocol for the knee.
TLDR
The OAI knee MRI protocol provides imaging data on multiple articular structures and features relevant to knee OA that will support a broad range of existing and anticipated measurement methods while balancing requirements for high image quality and consistency against the practical considerations of a large multi-center cohort study. Expand
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