M. Neitz

Publications275
h-index44
Citations6,749
Highly Influential Citations273
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Organization of the Human Trichromatic Cone Mosaic
TLDR
The results suggest that the assignment of L and M pigment, although highly irregular, is not a completely random process, and in the protan carrier, there was no evidence of clumping, perhaps as a result of cone migration during foveal development.
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Trichromatic colour vision in New World monkeys
TLDR
It is reported that multiple X-chromosome pigment genes and trichromatic colour vision are the norm for one genus of platyrrhine monkey, the howler monkey, Alouatta.
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Spectral tuning of pigments underlying red-green color vision.
TLDR
Comparisons of the deduced amino acid sequences suggest that three amino acid substitutions produce the approximately 30-nanometer difference in spectral peaks of the pigments underlying human red-green color vision, and red shifts of specific magnitudes are produced by replacement of nonpolar with hydroxyl-bearing amino acids at each of the three critical positions.
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Functional consequences of the relative numbers of L and M cones.
TLDR
This study examines the functional consequences of variation in the relative numbers of L and M cones (L/M cone ratio) for two observers whose ratios were measured by direct imaging and indicates that neural factors play an important role in stabilizing unique yellow against variation inThe L/M cones ratio.
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Color Perception Is Mediated by a Plastic Neural Mechanism that Is Adjustable in Adults
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Mutations in S-cone pigment genes and the absence of colour vision in two species of nocturnal primate
TLDR
Examination of the nucleotide sequences of the S-cone pigment genes reveals that each species has deleterious mutational changes: in comparison to the sequence for the corresponding region of the human gene, exon 4 of the bushbaby S- cone pigment gene has a two nucleotide deletion and a single nucleotide insertion that produces a frame shift and results in the introduction of a stop codon.
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The genetics of normal and defective color vision
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Estimates of L:M cone ratio from ERG flicker photometry and genetics.
TLDR
Estimates of L:M cone ratio for males with normal color vision were derived using the flicker-photometric electroretinogram (ERG), and extreme cone contribution ratios were found to be associated with atypical L-pigment amino acid combinations.
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Photoreceptor structure and function in patients with congenital achromatopsia.
TLDR
The current approach of using high-resolution techniques to assess photoreceptor structure and function in patients with achromatopsia should be useful in guiding selection of patients for future therapeutic trials as well as monitoring therapeutic response in these trials.
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Functional photoreceptor loss revealed with adaptive optics: an alternate cause of color blindness.
TLDR
Adaptive optics retinal imaging has revealed a mechanism for producing dichromatic color vision in which the expression of a mutant cone photopigment gene leads to the loss of the entire corresponding class of cone photoreceptor cells.
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