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MEGA5: molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods.
Comparative analysis of molecular sequence data is essential for reconstructing the evolutionary histories of species and inferring the nature and extent of selective forces shaping the evolution ofExpand
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MEGA4: Molecular Evolutionary Genetics Analysis (MEGA) software version 4.0.
We announce the release of the fourth version of MEGA software, which expands on the existing facilities for editing DNA sequence data from autosequencers, mining Web-databases, performing automaticExpand
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The neighbor-joining method: a new method for reconstructing phylogenetic trees.
  • N. Saitou, M. Nei
  • Biology, Medicine
  • Molecular biology and evolution
  • 1 July 1987
A new method called the neighbor-joining method is proposed for reconstructing phylogenetic trees from evolutionary distance data. The principle of this method is to find pairs of operationalExpand
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MEGA3: Integrated software for Molecular Evolutionary Genetics Analysis and sequence alignment
This paper provides an overview of the statistical methods, computational tools, and visual exploration modules for data input and the results obtainable in MEGA. Expand
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Molecular Evolutionary Genetics
Recent developments of statistical methods in molecular phylogenetics are reviewed. It is shown that the mathematical foundations of these methods are not well established, but computer simulationsExpand
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Estimation of average heterozygosity and genetic distance from a small number of individuals.
  • M. Nei
  • Biology, Medicine
  • Genetics
  • 20 July 1978
The magnitudes of the systematic biases involved in sample heterozygosity and sample genetic distances are evaluated, and formulae for obtaining unbiased estimates of average heterozygosity andExpand
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  • 1669
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MEGA2: molecular evolutionary genetics analysis software
We have developed a new software package, Molecular Evolutionary Genetics Analysis version 2 (MEGA2), for exploring and analyzing aligned DNA or protein sequences from an evolutionary perspective. Expand
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  • 1604
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Analysis of gene diversity in subdivided populations.
  • M. Nei
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences…
  • 1 December 1973
A method is presented by which the gene diversity (heterozygosity) of a subdivided population can be analyzed into its components, i.e., the gene diversities within and between subpopulations. ThisExpand
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  • 1177
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Estimation of the number of nucleotide substitutions in the control region of mitochondrial DNA in humans and chimpanzees.
  • K. Tamura, M. Nei
  • Biology, Medicine
  • Molecular biology and evolution
  • 1 May 1993
Examining the pattern of nucleotide substitution for the control region of mitochondrial DNA (mtDNA) in humans and chimpanzees, we developed a new mathematical method for estimating the number ofExpand
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Genetic Distance between Populations
  • M. Nei
  • Biology
  • The American Naturalist
  • 1 May 1972
A measure of genetic distance (D) based on the identity of genes between populations is formulated. It is defined as D = -logeI, where I is the normalized identity of genes between two populations.Expand
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