• Publications
  • Influence
MEGA5: molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods.
TLDR
The newest addition in MEGA5 is a collection of maximum likelihood (ML) analyses for inferring evolutionary trees, selecting best-fit substitution models, inferring ancestral states and sequences, and estimating evolutionary rates site-by-site. Expand
MEGA4: Molecular Evolutionary Genetics Analysis (MEGA) software version 4.0.
TLDR
Version 4 of MEGA software expands on the existing facilities for editing DNA sequence data from autosequencers, mining Web-databases, performing automatic and manual sequence alignment, analyzing sequence alignments to estimate evolutionary distances, inferring phylogenetic trees, and testing evolutionary hypotheses. Expand
The neighbor-joining method: a new method for reconstructing phylogenetic trees.
  • N. Saitou, M. Nei
  • Biology, Medicine
  • Molecular biology and evolution
  • 1 July 1987
TLDR
The neighbor-joining method and Sattath and Tversky's method are shown to be generally better than the other methods for reconstructing phylogenetic trees from evolutionary distance data. Expand
MEGA3: Integrated software for Molecular Evolutionary Genetics Analysis and sequence alignment
TLDR
An overview of the statistical methods, computational tools, and visual exploration modules for data input and the results obtainable in MEGA is provided. Expand
Molecular Evolutionary Genetics
TLDR
Recent developments of statistical methods in molecular phylogenetics are reviewed and it is shown that the mathematical foundations of these methods are not well established, but computer simulations and empirical data indicate that currently used methods produce reasonably good phylogenetic trees when a sufficiently large number of nucleotides or amino acids are used. Expand
Estimation of average heterozygosity and genetic distance from a small number of individuals.
  • M. Nei
  • Biology, Medicine
  • Genetics
  • 20 July 1978
TLDR
It is shown that the number of individuals to be used for estimating average heterozygosity can be very small if a large number of loci are studied and the average heter homozygosity is low. Expand
MEGA2: molecular evolutionary genetics analysis software
TLDR
MEGA2 vastly extends the capabilities of MEGA version 1 by facilitating analyses of large datasets, enabling creation and analyses of groups of sequences, and expanding the repertoire of statistical methods for molecular evolutionary studies. Expand
Estimation of the number of nucleotide substitutions in the control region of mitochondrial DNA in humans and chimpanzees.
  • K. Tamura, M. Nei
  • Biology, Medicine
  • Molecular biology and evolution
  • 1 May 1993
TLDR
A new mathematical method for estimating the number of transitional and transversional substitutions per site, as well as the total number of nucleotide substitutions, suggested that the transition/transversion ratio for the entire control region was approximately 15 and nearly the same for the two species. Expand
Genetic Distance between Populations
  • M. Nei
  • Biology
  • The American Naturalist
  • 2 April 1972
TLDR
If enough data are available, genetic distance between any pair of organisms can be measured in terms of D, and this measure is applicable to any kind of organism without regard to ploidy or mating scheme. Expand
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