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Evidence for a Complex Influence of Nicotinic Acetylcholine Receptors on Hippocampal Serotonin Release
Abstract: The effects of nicotine on 5‐hydroxytryptamine (5‐HT)release from serotonergic nerve endings in rat dorsal hippocampal slices werestudied. Nicotine (50‐500 μM) caused aExpand
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Unique allosteric regulation of 5-hydroxytryptamine receptor-mediated signal transduction by oleamide.
The effects of oleamide, an amidated lipid isolated from the cerebrospinal fluid of sleep-deprived cats, on serotonin receptor-mediated responses were investigated in cultured mammalian cells. In ratExpand
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Effects of Ischaemia on Neurotransmitter Release from the Isolated Retina
Abstract: The effects of “ischaemia” (glucose‐free Krebs‐bicarbonate medium gassed with N2/CO2 on the release of glutamate and other major neurotransmitters in the retina were examined using theExpand
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Modulation of extracellular GABA levels in the retina by activation of glial P2X‐purinoceptors
In the rat retina, γ‐aminobutyric acid (GABA) released as a transmitter is inactivated by uptake mainly into glial cells (Müller cells). Activation of P2‐purinoceptors in Müller cells increasesExpand
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THE UPTAKE OF [3H]GABA BY SLICES OF RAT CEREBRAL CORTEX
—A rapid accumulation of [3H]GABA occurs in slices of rat cerebral cortex incubated at 25° or 37° in a medium containing [3H]GABA. Tissue medium ratios of almost 100:1 are attained after a 60 minExpand
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Immunocytochemical evidence that vigabatrin in rats causes GABA accumulation in glial cells of the retina
Vigabatrin (gamma-vinyl-GABA, GVG) is an irreversible inhibitor of GABA-aminotransferase (GABA-T) that is under clinical trial as an antiepileptic drug. Rats were injected (i.p.) with GVG and killedExpand
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Effect of excitatory amino acids and analogues on [3H]acetylcholine release from amacrine cells of the rabbit retina.
The pharmacology of cholinergic amacrine cells has been further studied by examining the effects of excitatory amino acids and antagonists on [3H]acetylcholine (ACh) release from the retinas ofExpand
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Expression of αB‐crystallin in a mouse model of inherited retinal degeneration
αB-CRYSTALLIN, which is abundantly expressed in the lens but also in a diversity of other tissues, functions as a stress-inducible molecular chaperone and is increased in brain neurodegenerativeExpand
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Nitric oxide release is induced by dopamine during illumination of the carp retina: serial neurochemical control of light adaptation
Several lines of indirect evidence have suggested that nitric oxide may play an important role during light adaptation of the vertebrate retina. We aimed to verify directly the effect of light onExpand
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l-Homocysteic acid — A possible bipolar cell transmitter in the rabbit retina
The identity of the retinal bipolar cell transmitter(s) is unknown although there is much indirect evidence that suggests it may be glutamate or a related compound. Some bipolar cells synapse ontoExpand
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