• Publications
  • Influence
An anorexic lipid mediator regulated by feeding
Oleylethanolamide (OEA) is a natural analogue of the endogenous cannabinoid anandamide. Like anandamide, OEA is produced in cells in a stimulus-dependent manner and is rapidly eliminated by enzymaticExpand
  • 617
  • 43
A Peripheral Mechanism for CB1 Cannabinoid Receptor-Dependent Modulation of Feeding
Recent studies suggest that the endocannabinoid system modulates feeding. Despite the existence of central mechanisms for the regulation of food intake by endocannabinoids, evidence indicates thatExpand
  • 471
  • 43
  • PDF
Dopamine activation of endogenous cannabinoid signaling in dorsal striatum
We measured endogenous cannabinoid release in dorsal striatum of freely moving rats by microdialysis and gas chromatography/mass spectrometry. Neural activity stimulated the release of anandamide,Expand
  • 526
  • 28
Reversal of Dopamine D2 Receptor Responses by an Anandamide Transport Inhibitor
We characterized the pharmacological properties of the anandamide transport inhibitorN-(4-hydroxyphenyl)-arachidonamide (AM404) in rats and investigated the effects of this drug on behavioralExpand
  • 224
  • 19
  • PDF
Cannabinoid CB1 receptor antagonism reduces conditioned reinstatement of ethanol‐seeking behavior in rats
The endocannabinoid system is involved in a variety of effects of drugs of misuse, and blockade of the cannabinoid CB1 receptor by selective antagonists elicits marked reductions in opioid andExpand
  • 129
  • 13
The endocannabinoid system: physiology and pharmacology.
The endogenous cannabinoid system is an ubiquitous lipid signalling system that appeared early in evolution and which has important regulatory functions throughout the body in all vertebrates. TheExpand
  • 311
  • 11
  • PDF
CB1 cannabinoid receptor antagonist‐induced opiate withdrawal in morphine‐dependent rats
RECENT reports have provided evidence of a link between the endogenous brain cannabinoid system and the endogenous central opioid systems. Here we report that the selective CB1 receptor antagonist SRExpand
  • 142
  • 8
Regulation of brain anandamide by acute administration of ethanol.
The endogenous cannabinoid acylethanolamide AEA (arachidonoylethanolamide; also known as anandamide) participates in the neuroadaptations associated with chronic ethanol exposure. However, no studiesExpand
  • 89
  • 7
  • PDF
Long-term behavioral effects of perinatal exposure to delta 9-tetrahydrocannabinol in rats: possible role of pituitary-adrenal axis.
This work evaluated motor behaviors in adult male and female rats exposed to delta 9-tetrahydrocannabinol (THC, 5 mg/kg) during gestation and lactation. The possibility that perinatal THC exposureExpand
  • 62
  • 7
Corticotropin-releasing factor (CRF) antagonist [D-Phe12,Nle21,38,C alpha MeLeu37]CRF attenuates the acute actions of the highly potent cannabinoid receptor agonist HU-210 on defensive-withdrawal
The present study evaluated the modulatory role of central corticotropin-releasing factor (CRF) systems in the mediation of the effects of acute exposure to the brain cannabinoid receptor agonistExpand
  • 169
  • 6