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Bioactive compounds produced by cyanobacteria
The close similarity or identity in structures between cyanobacterial products and compounds isolated from sponges, tunicates and other marine invertebrates suggests the latter compounds may be derived from dietary or symbiotic blue-green algae. Expand
Hepatotoxic microcystin diversity in cyanobacterial blooms collected in portuguese freshwaters
Significant relationships between LD 50 -MCYST-LR-total MCYST content were found and the need for monitoring cyanobacteria and their toxins in eutrophic waters that are used for drinking and recreation purposes is discussed. Expand
Structure and biosynthesis of toxins from blue-green algae (cyanobacteria)
Nearly 30 new microcystins have been isolated in the laboratory from cyanobacteria species and their structures assigned, largely employing tandem FAB mass spectrometry (FABMS/CID/MS) and numerous analogs identified or synthesized allow the identification of important parameters in a structure-activity relationship study. Expand
Isolation and characterization of a variety of microcystins from seven strains of the cyanobacterial genus Anabaena.
Hepatotoxins (microcystins) from seven freshwater Anabaena strains originating from three different Finnish lakes and one lake in Norway were isolated by high-performance liquid chromatography andExpand
Isolation and characterization of hepatotoxic microcystin homologs from the filamentous freshwater cyanobacterium Nostoc sp. strain 152.
Analysis showed that the toxins isolated from a lake in Finland were new types of microcystin-LR homologs, and the toxicities were not significantly different from those of micro CystIn-LR or demethylmicrocyst in-LR. Expand
Three new microcystins, cyclic heptapeptide hepatotoxins, from Nostoc sp. strain 152.
Three new cyclic heptapeptide hepatotoxins were isolated from the cyanobacterium Nostoc sp. Expand
Simultaneous production of homoanatoxin-a, anatoxin-a, and a new non-toxic 4-hydroxyhomoanatoxin-a by the cyanobacterium Raphidiopsis mediterranea Skuja.
This is the first report demonstrating the simultaneous production of anatoxin-a and homoanat toxin-a by the same strain of cyanobacterium, and the procedures were effective in removing impurities and concentrating alkaloidal neurotoxins. Expand
[D-Leu(1)] microcystin-LR, a new microcystin isoplated from waterbloom in a Canadian prairie lake.
This is the first microcystin identified, among the 64 knownmicrocystins, that has both a D- and L-Leu amino acid. Expand